| Transactions |
| Date | Team | Player | Type | OthTm | EffDate | When |
| 3/31/2005 | FOR | Ohka | Acquired via trade | SCO | | After |
| 3/31/2005 | HEN | Vogelsong | Traded away | SLG | | After |
| 3/31/2005 | HEN | Williams | Acquired via trade | SLG | | After |
| 3/31/2005 | SLG | Vogelsong | Acquired via trade | HEN | | After |
| 3/31/2005 | SLG | Williams | Traded away | HEN | | After |
| 4/7/2005 | BST | Franco | Promoted to active roster | | | Before |
| 4/7/2005 | BST | Gload | Demoted to reserve roster | | | Before |
| 4/7/2005 | COM | Cota | Promoted to active roster | | | Before |
| 4/7/2005 | COM | DeJean | Demoted to reserve roster | | | Before |
| 4/7/2005 | COM | DeJean | Promoted to active roster | | | Before |
| 4/7/2005 | COM | Elarton | Demoted to reserve roster | | | Before |
| 4/7/2005 | COM | Fossum | Promoted to active roster | | | Before |
| 4/7/2005 | COM | Jones | Demoted to reserve roster | | | Before |
| 4/7/2005 | COM | Jones | Promoted to active roster | | | Before |
| 4/7/2005 | COM | Marrero | Demoted to reserve roster | | | Before |
| 4/7/2005 | HEN | Rhodes | Promoted to active roster | | | Before |
| 4/7/2005 | HEN | Williamson | Demoted to reserve roster | | | Before |
| 4/7/2005 | SLG | Castro | Signed | | | Before |
| 4/7/2005 | SLG | Griffey | Demoted to reserve roster | | | Before |
| 4/7/2005 | SLG | House | Released | | | Before |
| 4/12/2005 | COM | Armas | Promoted to active roster | | | Before |
| 4/12/2005 | COM | DeJean | Promoted to active roster | | | Before |
| 4/12/2005 | COM | Elarton | Promoted to active roster | | | Before |
| 4/12/2005 | COM | Fossum | Demoted to reserve roster | | | Before |
| 4/12/2005 | COM | Haren | Demoted to reserve roster | | | Before |
| 4/12/2005 | COM | Jones | Demoted to reserve roster | | | Before |
| 4/12/2005 | COM | Loaiza | Promoted to active roster | | | Before |
| 4/12/2005 | COM | Patterson | Demoted to reserve roster | | | Before |
| 4/12/2005 | COM | Wolf | Demoted to reserve roster | | | Before |
| 4/12/2005 | COM | Marrero | Traded away | SYN | | After |
| 4/12/2005 | COM | Patterson | Acquired via trade | SYN | | After |
| 4/12/2005 | HYS | Bedard | Demoted to reserve roster | | | Before |
| 4/12/2005 | HYS | Benoit | Promoted to active roster | | | Before |
| 4/12/2005 | HYS | Lopez | Promoted to active roster | | | Before |
| 4/12/2005 | HYS | Perez | Demoted to reserve roster | | | Before |
| 4/12/2005 | HYS | Wilson | Demoted to reserve roster | | | Before |
| 4/12/2005 | HYS | Wilson | Promoted to active roster | | | Before |
| 4/12/2005 | SYN | Marrero | Acquired via trade | COM | | After |
| 4/12/2005 | SYN | Patterson | Traded away | COM | | After |
| 4/14/2005 | BST | Beltran,F | Promoted to active roster | | | Before |
| 4/14/2005 | BST | Colon | Promoted to active roster | | | Before |
| 4/14/2005 | BST | Franco | Demoted to reserve roster | | | Before |
| 4/14/2005 | BST | Guardado | Demoted to reserve roster | | | Before |
| 4/14/2005 | FOR | Ohka | Demoted to reserve roster | | | Before |
| 4/14/2005 | FOR | Pettitte | Promoted to active roster | | | Before |
| 4/14/2005 | HYS | Grimsley | Demoted to reserve roster | | | Before |
| 4/14/2005 | HYS | Hill | Demoted to reserve roster | | | Before |
| 4/14/2005 | HYS | Miller | Promoted to active roster | | | Before |
| 4/14/2005 | HYS | Perez | Promoted to active roster | | | Before |
| 4/14/2005 | HYS | Tankersley | Promoted to active roster | | | Before |
| 4/14/2005 | HYS | Woodward | Demoted to reserve roster | | | Before |
| 4/14/2005 | SLG | Blanton | Promoted to active roster | | | Before |
| 4/14/2005 | SLG | Prior | Demoted to reserve roster | | | Before |
| 4/14/2005 | SLG | Vogelsong | Promoted to active roster | | | Before |
| 4/14/2005 | SLG | Wickman | Demoted to reserve roster | | | Before |
| 4/14/2005 | SYN | Cook | Demoted to reserve roster | | | Before |
| 4/14/2005 | SYN | German | Demoted to reserve roster | | | Before |
| 4/14/2005 | SYN | German | Promoted to active roster | | | Before |
| 4/14/2005 | SYN | German | Demoted to reserve roster | | | Before |
| 4/14/2005 | SYN | German | Promoted to active roster | | | Before |
| 4/14/2005 | SYN | Marrero | Promoted to active roster | | | Before |
| 4/14/2005 | SYN | Mauer | Promoted to active roster | | | Before |
| 4/14/2005 | SYN | Tsao | Demoted to reserve roster | | | Before |
| 4/14/2005 | SYN | Tsao | Promoted to active roster | | | Before |
| 4/14/2005 | SYN | Tsao | Promoted to active roster | | | Before |
| 4/14/2005 | SYN | Valentin | Demoted to reserve roster | | | Before |
| 4/20/2005 | COM | Cota | Demoted to reserve roster | | | Before |
| 4/20/2005 | COM | Dreifort | Demoted to reserve roster | | | Before |
| 4/20/2005 | COM | Haren | Promoted to active roster | | | Before |
| 4/20/2005 | COM | Jones | Promoted to active roster | | | Before |
| 4/20/2005 | FOR | Bocachica | Signed | | | Before |
| 4/20/2005 | FOR | Cabrera | Promoted to active roster | | | Before |
| 4/20/2005 | FOR | Ohka | Demoted to reserve roster | | | Before |
| 4/20/2005 | FOR | Ohka | Promoted to active roster | | | Before |
| 4/20/2005 | FOR | Pettitte | Demoted to reserve roster | | | Before |
| 4/20/2005 | FOR | Sanchez | Released | | | Before |
| 4/20/2005 | FOR | Sweeney | Demoted to reserve roster | | | Before |
| 4/20/2005 | FOR | Telemaco | Promoted to active roster | | | Before |
| 4/20/2005 | FOR | Witasick | Demoted to reserve roster | | | Before |
| 4/20/2005 | HEN | Cust | Signed | | | Before |
| 4/20/2005 | HEN | Cust | Demoted to reserve roster | | | Before |
| 4/20/2005 | HEN | Pascucci | Released | | | Before |
| 4/20/2005 | HEN | Rhodes | Demoted to reserve roster | | | Before |
| 4/20/2005 | HEN | Williamson | Promoted to active roster | | | Before |
| 4/20/2005 | SLG | Blanton | Demoted to reserve roster | | | Before |
| 4/20/2005 | SLG | Eischen | Promoted to active roster | | | Before |
| 4/20/2005 | SYN | Dominguez | Demoted to reserve roster | | | Before |
| 4/20/2005 | SYN | Dominguez | Promoted to active roster | | | Before |
| 4/20/2005 | SYN | German | Demoted to reserve roster | | | Before |
| 4/20/2005 | SYN | German | Promoted to active roster | | | Before |
| 4/20/2005 | SYN | Reyes | Promoted to active roster | | | Before |
| 4/20/2005 | SYN | Reyes | Demoted to reserve roster | | | Before |
| 4/20/2005 | SYN | Tsao | Demoted to reserve roster | | | Before |
| 4/20/2005 | SYN | Tsao | Promoted to active roster | | | Before |
| 4/25/2005 | HYS | Anderson | Promoted to active roster | | | Before |
| 4/25/2005 | HYS | Bedard | Promoted to active roster | | | Before |
| 4/25/2005 | HYS | Cedeno | Promoted to active roster | | | Before |
| 4/25/2005 | HYS | Choi | Demoted to reserve roster | | | Before |
| 4/25/2005 | HYS | Francis | Promoted to active roster | | | Before |
| 4/25/2005 | HYS | Grimsley | Promoted to active roster | | | Before |
| 4/25/2005 | HYS | Heilman | Demoted to reserve roster | | | Before |
| 4/25/2005 | HYS | Heilman | Promoted to active roster | | | Before |
| 4/25/2005 | HYS | Hill | Promoted to active roster | | | Before |
| 4/25/2005 | HYS | Infante | Demoted to reserve roster | | | Before |
| 4/25/2005 | HYS | Mecir | Demoted to reserve roster | | | Before |
| 4/25/2005 | HYS | Peavy | Demoted to reserve roster | | | Before |
| 4/25/2005 | HYS | Ross | Demoted to reserve roster | | | Before |
| 4/25/2005 | HYS | Wilson | Demoted to reserve roster | | | Before |
| 4/25/2005 | SYN | Dominguez | Promoted to active roster | | | Before |
| 4/25/2005 | SYN | German | Promoted to active roster | | | Before |
| 4/25/2005 | SYN | Larkin | Demoted to reserve roster | | | Before |
| 4/25/2005 | SYN | Mauer | Demoted to reserve roster | | | Before |
| 4/25/2005 | SYN | Reyes | Demoted to reserve roster | | | Before |
| 4/25/2005 | SYN | Reyes | Promoted to active roster | | | Before |
| 4/25/2005 | SYN | Tsao | Demoted to reserve roster | | | Before |
| 4/25/2005 | SYN | Valentin | Promoted to active roster | | | Before |
| 4/27/2005 | BST | Guardado | Promoted to active roster | | | Before |
| 4/27/2005 | BST | Wood | Demoted to reserve roster | | | Before |
| 4/27/2005 | COM | Armas | Demoted to reserve roster | | | Before |
| 4/27/2005 | COM | Cota | Promoted to active roster | | | Before |
| 4/27/2005 | COM | DeJean | Demoted to reserve roster | | | Before |
| 4/27/2005 | COM | Dreifort | Promoted to active roster | | | Before |
| 4/27/2005 | COM | Fossum | Promoted to active roster | | | Before |
| 4/27/2005 | COM | Haren | Demoted to reserve roster | | | Before |
| 4/27/2005 | COM | Loaiza | Demoted to reserve roster | | | Before |
| 4/27/2005 | COM | Wolf | Promoted to active roster | | | Before |
| 4/27/2005 | FOR | Cerda | Demoted to reserve roster | | | Before |
| 4/27/2005 | FOR | Delgado | Demoted to reserve roster | | | Before |
| 4/27/2005 | FOR | Delgado | Promoted to active roster | | | Before |
| 4/27/2005 | FOR | Ohka | Promoted to active roster | | | Before |
| 4/27/2005 | FOR | Saarloos | Demoted to reserve roster | | | Before |
| 4/27/2005 | FOR | Witasick | Promoted to active roster | | | Before |
| 4/27/2005 | HEN | Davis | Promoted to active roster | | | Before |
| 4/27/2005 | HEN | Redmond | Demoted to reserve roster | | | Before |
| 4/27/2005 | HEN | Rhodes | Promoted to active roster | | | Before |
| 4/27/2005 | HEN | Sanchez | Demoted to reserve roster | | | Before |
| 4/27/2005 | HYS | Anderson | Demoted to reserve roster | | | Before |
| 4/27/2005 | HYS | Cedeno | Demoted to reserve roster | | | Before |
| 4/27/2005 | HYS | Choi | Promoted to active roster | | | Before |
| 4/27/2005 | HYS | Infante | Promoted to active roster | | | Before |
| 4/27/2005 | HYS | Miller | Demoted to reserve roster | | | Before |
| 4/27/2005 | HYS | Peavy | Promoted to active roster | | | Before |
| 4/27/2005 | HYS | Tankersley | Demoted to reserve roster | | | Before |
| 4/27/2005 | HYS | Wilson | Promoted to active roster | | | Before |
| 4/27/2005 | SLG | Donnelly | Demoted to reserve roster | | | Before |
| 4/27/2005 | SLG | Wickman | Promoted to active roster | | | Before |
| 5/2/2005 | COM | Affeldt | Demoted to reserve roster | | | Before |
| 5/2/2005 | COM | Armas | Promoted to active roster | | | Before |
| 5/2/2005 | COM | DeJean | Promoted to active roster | | | Before |
| 5/2/2005 | COM | Elarton | Demoted to reserve roster | | | Before |
| 5/2/2005 | COM | Fossum | Demoted to reserve roster | | | Before |
| 5/2/2005 | COM | Loaiza | Promoted to active roster | | | Before |
| 5/2/2005 | HEN | Garcia,D | Promoted to active roster | | | Before |
| 5/2/2005 | HEN | Wright | Demoted to reserve roster | | | Before |
| 5/3/2005 | BST | Cotts | Promoted to active roster | | | Before |
| 5/3/2005 | BST | Hendrickson | Demoted to reserve roster | | | Before |
| 5/3/2005 | BST | Miller | Demoted to reserve roster | | | Before |
| 5/3/2005 | BST | Navarro | Promoted to active roster | | | Before |
| 5/3/2005 | FOR | Barmes | Demoted to reserve roster | | | Before |
| 5/3/2005 | FOR | Cerda | Promoted to active roster | | | Before |
| 5/3/2005 | FOR | Delgado | Promoted to active roster | | | Before |
| 5/3/2005 | FOR | Ohka | Demoted to reserve roster | | | Before |
| 5/3/2005 | FOR | Pettitte | Promoted to active roster | | | Before |
| 5/3/2005 | FOR | Telemaco | Demoted to reserve roster | | | Before |
| 5/3/2005 | HYS | Anderson | Promoted to active roster | | | Before |
| 5/3/2005 | HYS | Benoit | Demoted to reserve roster | | | Before |
| 5/3/2005 | HYS | Carrasco | Promoted to active roster | | | Before |
| 5/3/2005 | HYS | Choi | Demoted to reserve roster | | | Before |
| 5/3/2005 | HYS | Heilman | Promoted to active roster | | | Before |
| 5/3/2005 | HYS | Miller | Promoted to active roster | | | Before |
| 5/3/2005 | HYS | Molina,J | Demoted to reserve roster | | | Before |
| 5/3/2005 | HYS | Peavy | Demoted to reserve roster | | | Before |
| 5/3/2005 | HYS | Perez | Demoted to reserve roster | | | Before |
| 5/3/2005 | HYS | Perisho | Demoted to reserve roster | | | Before |
| 5/3/2005 | HYS | Ross | Promoted to active roster | | | Before |
| 5/3/2005 | HYS | Woodward | Promoted to active roster | | | Before |
| 5/3/2005 | SLG | Betemit | Promoted to active roster | | | Before |
| 5/3/2005 | SLG | Grudzielanek | Demoted to reserve roster | | | Before |
| 5/3/2005 | SLG | Kroeger | Promoted to active roster | | | Before |
| 5/3/2005 | SLG | Wickman | Demoted to reserve roster | | | Before |
| 5/8/2005 | FOR | Castillo | Demoted to reserve roster | | | Before |
| 5/8/2005 | FOR | Cerda | Demoted to reserve roster | | | Before |
| 5/8/2005 | FOR | Neal | Promoted to active roster | | | Before |
| 5/8/2005 | FOR | Ohka | Promoted to active roster | | | Before |
| 5/8/2005 | FOR | Pettitte | Demoted to reserve roster | | | Before |
| 5/8/2005 | FOR | Sweeney | Promoted to active roster | | | Before |
| 5/8/2005 | FOR | Telemaco | Promoted to active roster | | | Before |
| 5/8/2005 | FOR | Witasick | Demoted to reserve roster | | | Before |
| 5/10/2005 | BLU | Hall | Demoted to reserve roster | | | Before |
| 5/10/2005 | BLU | Hall | Promoted to active roster | | | Before |
| 5/10/2005 | BLU | Hall | Promoted to active roster | | | Before |
| 5/10/2005 | BLU | Lopez,J | Demoted to reserve roster | | | Before |
| 5/10/2005 | BLU | Lopez,J | Promoted to active roster | | | Before |
| 5/10/2005 | BLU | Lopez,J | Demoted to reserve roster | | | Before |
| 5/10/2005 | BST | Jordan | Promoted to active roster | | | Before |
| 5/10/2005 | BST | Navarro | Demoted to reserve roster | | | Before |
| 5/10/2005 | COM | Affeldt | Promoted to active roster | | | Before |
| 5/10/2005 | COM | Armas | Demoted to reserve roster | | | Before |
| 5/10/2005 | COM | Elarton | Promoted to active roster | | | Before |
| 5/10/2005 | COM | Gryboski | Demoted to reserve roster | | | Before |
| 5/10/2005 | COM | Haren | Promoted to active roster | | | Before |
| 5/10/2005 | COM | Loaiza | Demoted to reserve roster | | | Before |
| 5/10/2005 | COM | Patterson | Promoted to active roster | | | Before |
| 5/10/2005 | COM | Wolf | Demoted to reserve roster | | | Before |
| 5/10/2005 | FOR | Castillo | Released | | | Before |
| 5/10/2005 | FOR | Ojeda | Signed | | | Before |
| 5/10/2005 | HSX | Colome | Demoted to reserve roster | | | Before |
| 5/10/2005 | HSX | Liriano | Promoted to active roster | | | Before |
| 5/10/2005 | HYS | Benoit | Promoted to active roster | | | Before |
| 5/10/2005 | HYS | Carrasco | Demoted to reserve roster | | | Before |
| 5/10/2005 | HYS | Choi | Promoted to active roster | | | Before |
| 5/10/2005 | HYS | Francis | Demoted to reserve roster | | | Before |
| 5/10/2005 | HYS | Heilman | Demoted to reserve roster | | | Before |
| 5/10/2005 | HYS | Molina,J | Promoted to active roster | | | Before |
| 5/10/2005 | HYS | Peavy | Promoted to active roster | | | Before |
| 5/10/2005 | HYS | Perisho | Promoted to active roster | | | Before |
| 5/10/2005 | HYS | Ross | Demoted to reserve roster | | | Before |
| 5/10/2005 | HYS | Teixeira | Demoted to reserve roster | | | Before |
| 5/10/2005 | HYS | Teixeira | Promoted to active roster | | | Before |
| 5/10/2005 | HYS | Woodward | Demoted to reserve roster | | | Before |
| 5/10/2005 | SLG | Betemit | Demoted to reserve roster | | | Before |
| 5/10/2005 | SLG | Grudzielanek | Promoted to active roster | | | Before |
| 5/16/2005 | BOU | Ainsworth | Promoted to active roster | | | Before |
| 5/16/2005 | BOU | Rauch | Demoted to reserve roster | | | Before |
| 5/16/2005 | COM | Affeldt | Demoted to reserve roster | | | Before |
| 5/16/2005 | COM | DeJean | Demoted to reserve roster | | | Before |
| 5/16/2005 | COM | Fossum | Promoted to active roster | | | Before |
| 5/16/2005 | COM | Gryboski | Promoted to active roster | | | Before |
| 5/16/2005 | FOR | Cerda | Promoted to active roster | | | Before |
| 5/16/2005 | FOR | Neal | Demoted to reserve roster | | | Before |
| 5/16/2005 | SLG | Donnelly | Promoted to active roster | | | Before |
| 5/16/2005 | SLG | Eischen | Demoted to reserve roster | | | Before |
| 5/16/2005 | SLG | Hancock | Demoted to reserve roster | | | Before |
| 5/16/2005 | SLG | Hunter | Demoted to reserve roster | | | Before |
| 5/16/2005 | SLG | Prior | Promoted to active roster | | | Before |
| 5/16/2005 | SLG | Restovich | Promoted to active roster | | | Before |
| 5/16/2005 | SYN | Hairston | Demoted to reserve roster | | | Before |
| 5/16/2005 | SYN | Larkin | Promoted to active roster | | | Before |
| 5/21/2005 | BLU | Ayala | Promoted to active roster | | | Before |
| 5/21/2005 | BLU | Farnsworth | Demoted to reserve roster | | | Before |
| 5/21/2005 | HYS | Cedeno | Promoted to active roster | | | Before |
| 5/21/2005 | HYS | Greene | Demoted to reserve roster | | | Before |
| 5/21/2005 | HYS | Lopez | Demoted to reserve roster | | | Before |
| 5/21/2005 | HYS | Mecir | Promoted to active roster | | | Before |
| 5/21/2005 | HYS | Miller | Demoted to reserve roster | | | Before |
| 5/21/2005 | HYS | Perez | Promoted to active roster | | | Before |
| 5/21/2005 | HYS | Ross | Promoted to active roster | | | Before |
| 5/21/2005 | HYS | White | Demoted to reserve roster | | | Before |
| 5/23/2005 | BOU | Garcia | Promoted to active roster | | | Before |
| 5/23/2005 | BOU | Rodriguez | Demoted to reserve roster | | | Before |
| 5/23/2005 | COM | Affeldt | Promoted to active roster | | | Before |
| 5/23/2005 | COM | Armas | Promoted to active roster | | | Before |
| 5/23/2005 | COM | DeJean | Promoted to active roster | | | Before |
| 5/23/2005 | COM | Elarton | Demoted to reserve roster | | | Before |
| 5/23/2005 | COM | Fossum | Demoted to reserve roster | | | Before |
| 5/23/2005 | COM | Gryboski | Demoted to reserve roster | | | Before |
| 5/23/2005 | COM | Haren | Demoted to reserve roster | | | Before |
| 5/23/2005 | COM | Loaiza | Promoted to active roster | | | Before |
| 5/23/2005 | COM | Patterson | Demoted to reserve roster | | | Before |
| 5/23/2005 | COM | Wolf | Promoted to active roster | | | Before |
| 5/23/2005 | FOR | Knotts | Released | | | Before |
| 5/23/2005 | FOR | Laker | Signed | | | Before |
| 5/23/2005 | FOR | McPherson | Demoted to reserve roster | | | Before |
| 5/23/2005 | FOR | Neal | Promoted to active roster | | | Before |
| 5/23/2005 | FOR | Ohka | Demoted to reserve roster | | | Before |
| 5/23/2005 | FOR | Pettitte | Promoted to active roster | | | Before |
| 5/23/2005 | FOR | Ransom | Signed | | | Before |
| 5/23/2005 | FOR | Rincon | Demoted to reserve roster | | | Before |
| 5/23/2005 | FOR | Sweeney | Demoted to reserve roster | | | Before |
| 5/23/2005 | FOR | Sweeney | Promoted to active roster | | | Before |
| 5/23/2005 | FOR | Telemaco | Released | | | Before |
| 5/23/2005 | FOR | Walker | Demoted to reserve roster | | | Before |
| 5/23/2005 | FOR | Witasick | Promoted to active roster | | | Before |
| 5/23/2005 | HSX | Capellan | Promoted to active roster | | | Before |
| 5/23/2005 | HSX | Kline | Demoted to reserve roster | | | Before |
| 5/23/2005 | SLG | Griffey | Promoted to active roster | | | Before |
| 5/23/2005 | SLG | Hunter | Promoted to active roster | | | Before |
| 5/23/2005 | SLG | Kroeger | Demoted to reserve roster | | | Before |
| 5/23/2005 | SLG | Restovich | Demoted to reserve roster | | | Before |
| 5/23/2005 | SYN | Hairston | Promoted to active roster | | | Before |
| 5/23/2005 | SYN | Reyes | Demoted to reserve roster | | | Before |
| 5/28/2005 | FOR | Wright | Acquired via trade | PHO | | After |
| 5/28/2005 | HEN | Hawkins | Traded away | SCO | | After |
| 5/28/2005 | HEN | Hawkins | Acquired via trade | SCO | | After |
| 5/28/2005 | HEN | Hawkins | Acquired via trade | SCO | | After |
| 5/29/2005 | BLU | Floyd | Promoted to active roster | | | Before |
| 5/29/2005 | BLU | Valdez | Demoted to reserve roster | | | Before |
| 5/29/2005 | COM | Armas | Demoted to reserve roster | | | Before |
| 5/29/2005 | COM | Brazoban | Demoted to reserve roster | | | Before |
| 5/29/2005 | COM | Cota | Demoted to reserve roster | | | Before |
| 5/29/2005 | COM | Elarton | Promoted to active roster | | | Before |
| 5/29/2005 | COM | Fossum | Promoted to active roster | | | Before |
| 5/29/2005 | COM | Gryboski | Promoted to active roster | | | Before |
| 5/29/2005 | COM | Haren | Promoted to active roster | | | Before |
| 5/29/2005 | COM | Loaiza | Demoted to reserve roster | | | Before |
| 5/29/2005 | COM | Patterson | Promoted to active roster | | | Before |
| 5/29/2005 | COM | Ponson | Demoted to reserve roster | | | Before |
| 5/29/2005 | FOR | Cabrera | Demoted to reserve roster | | | Before |
| 5/29/2005 | FOR | Cabrera | Promoted to active roster | | | Before |
| 5/29/2005 | FOR | McPherson | Promoted to active roster | | | Before |
| 5/29/2005 | FOR | Pettitte | Demoted to reserve roster | | | Before |
| 5/29/2005 | FOR | Ransom | Demoted to reserve roster | | | Before |
| 5/29/2005 | FOR | Ransom | Promoted to active roster | | | Before |
| 5/29/2005 | FOR | Ransom | Demoted to reserve roster | | | Before |
| 5/29/2005 | FOR | Rincon | Promoted to active roster | | | Before |
| 5/29/2005 | FOR | Saarloos | Released | | | Before |
| 5/29/2005 | FOR | Witasick | Demoted to reserve roster | | | Before |
| 5/29/2005 | HEN | Bennett,G | Signed | | | Before |
| 5/29/2005 | HEN | Davis | Demoted to reserve roster | | | Before |
| 5/29/2005 | HEN | Garcia,D | Demoted to reserve roster | | | Before |
| 5/29/2005 | HEN | Herges | Released | | | Before |
| 5/29/2005 | HEN | Pratt | Released | | | Before |
| 5/29/2005 | HEN | Redmond | Promoted to active roster | | | Before |
| 5/29/2005 | HEN | Rhodes | Promoted to active roster | | | Before |
| 5/29/2005 | HEN | Sanchez | Demoted to reserve roster | | | Before |
| 5/29/2005 | HEN | Williamson | Demoted to reserve roster | | | Before |
| 5/29/2005 | HSX | Graffanino | Demoted to reserve roster | | | Before |
| 5/29/2005 | HSX | Loe | Promoted to active roster | | | Before |
| 5/29/2005 | HSX | Putz | Demoted to reserve roster | | | Before |
| 5/29/2005 | HSX | Turnbow | Promoted to active roster | | | Before |
| 5/29/2005 | HSX | Vidro | Promoted to active roster | | | Before |
| 5/29/2005 | HSX | Wagner | Demoted to reserve roster | | | Before |
| 5/29/2005 | HYS | Cedeno | Demoted to reserve roster | | | Before |
| 5/29/2005 | HYS | Greene | Promoted to active roster | | | Before |
| 5/29/2005 | HYS | Lopez | Promoted to active roster | | | Before |
| 5/29/2005 | HYS | Miller | Demoted to reserve roster | | | Before |
| 5/29/2005 | HYS | Miller | Promoted to active roster | | | Before |
| 5/29/2005 | HYS | Molina,J | Demoted to reserve roster | | | Before |
| 5/29/2005 | HYS | Reitsma | Demoted to reserve roster | | | Before |
| 5/29/2005 | HYS | White | Promoted to active roster | | | Before |
| 5/29/2005 | SLG | Donnelly | Demoted to reserve roster | | | Before |
| 5/29/2005 | SLG | Griffey | Demoted to reserve roster | | | Before |
| 5/29/2005 | SLG | Kroeger | Demoted to reserve roster | | | Before |
| 5/29/2005 | SLG | Kroeger | Promoted to active roster | | | Before |
| 5/29/2005 | SLG | Restovich | Promoted to active roster | | | Before |
| 5/29/2005 | SLG | Wickman | Promoted to active roster | | | Before |
| 5/29/2005 | SYN | Mauer | Promoted to active roster | | | Before |
| 5/29/2005 | SYN | Valentin | Demoted to reserve roster | | | Before |
| 6/2/2005 | FOR | Bocachica | Demoted to reserve roster | | | Before |
| 6/5/2005 | BLU | Floyd | Demoted to reserve roster | | | Before |
| 6/5/2005 | BLU | Valdez | Promoted to active roster | | | Before |
| 6/5/2005 | BOU | Johnson | Demoted to reserve roster | | | Before |
| 6/5/2005 | BOU | Johnson | Promoted to active roster | | | Before |
| 6/5/2005 | BST | Cotts | Demoted to reserve roster | | | Before |
| 6/5/2005 | BST | Schoeneweis | Promoted to active roster | | | Before |
| 6/5/2005 | COM | Armas | Promoted to active roster | | | Before |
| 6/5/2005 | COM | Elarton | Demoted to reserve roster | | | Before |
| 6/5/2005 | COM | Haren | Demoted to reserve roster | | | Before |
| 6/5/2005 | COM | Loaiza | Promoted to active roster | | | Before |
| 6/5/2005 | COM | Patterson | Demoted to reserve roster | | | Before |
| 6/5/2005 | COM | Ponson | Promoted to active roster | | | Before |
| 6/5/2005 | FOR | Bocachica | Released | | | Before |
| 6/5/2005 | FOR | Cabrera | Demoted to reserve roster | | | Before |
| 6/5/2005 | FOR | Magruder | Signed | | | Before |
| 6/5/2005 | FOR | Neal | Demoted to reserve roster | | | Before |
| 6/5/2005 | FOR | Pettitte | Promoted to active roster | | | Before |
| 6/5/2005 | FOR | Sweeney | Demoted to reserve roster | | | Before |
| 6/5/2005 | FOR | Walker | Promoted to active roster | | | Before |
| 6/5/2005 | FOR | Witasick | Promoted to active roster | | | Before |
| 6/5/2005 | HEG | Easley | Demoted to reserve roster | | | Before |
| 6/5/2005 | HEG | Hernandez | Released | | | Before |
| 6/5/2005 | HEG | Lankford | Signed | | | Before |
| 6/5/2005 | HSX | Capellan | Demoted to reserve roster | | | Before |
| 6/5/2005 | HSX | Kline | Promoted to active roster | | | Before |
| 6/5/2005 | HSX | Loe | Demoted to reserve roster | | | Before |
| 6/5/2005 | HSX | Putz | Promoted to active roster | | | Before |
| 6/5/2005 | SLG | Hancock | Promoted to active roster | | | Before |
| 6/5/2005 | SLG | Vogelsong | Demoted to reserve roster | | | Before |
| 6/5/2005 | SLG | Wickman | Demoted to reserve roster | | | Before |
| 6/5/2005 | SLG | Wickman | Promoted to active roster | | | Before |
| 6/5/2005 | SYN | Cook | Promoted to active roster | | | Before |
| 6/5/2005 | SYN | Dominguez | Demoted to reserve roster | | | Before |
| 6/5/2005 | SYN | Graves | Demoted to reserve roster | | | Before |
| 6/5/2005 | SYN | Graves | Promoted to active roster | | | Before |
| 6/5/2005 | SYN | Larkin | Demoted to reserve roster | | | Before |
| 6/5/2005 | SYN | Ludwick | Promoted to active roster | | | Before |
| 6/5/2005 | SYN | Mauer | Promoted to active roster | | | Before |
| 6/5/2005 | SYN | Reyes | Promoted to active roster | | | Before |
| 6/5/2005 | SYN | Rivera | Demoted to reserve roster | | | Before |
| 6/5/2005 | SYN | Valentin | Demoted to reserve roster | | | Before |
| 6/8/2005 | FOR | Bocachica | Released | | | Before |
| 6/8/2005 | FOR | Bocachica | Signed | | | Before |
| 6/8/2005 | HEG | Hernandez | Released | | | Before |
| 6/8/2005 | HEG | Hernandez | Signed | | | Before |
| 6/10/2005 | HEG | Mirabelli | Promoted to active roster | | | Before |
| 6/10/2005 | HEG | Ojeda | Demoted to reserve roster | | | Before |
| 6/11/2005 | BLU | Blanco | Promoted to active roster | | | Before |
| 6/11/2005 | BLU | Diaz | Promoted to active roster | | | Before |
| 6/11/2005 | BLU | Mueller | Demoted to reserve roster | | | Before |
| 6/11/2005 | BLU | Perez | Demoted to reserve roster | | | Before |
| 6/11/2005 | BOU | Johnson | Promoted to active roster | | | Before |
| 6/11/2005 | BOU | Pena | Demoted to reserve roster | | | Before |
| 6/11/2005 | COM | Armas | Promoted to active roster | | | Before |
| 6/11/2005 | COM | Elarton | Demoted to reserve roster | | | Before |
| 6/11/2005 | COM | Haren | Demoted to reserve roster | | | Before |
| 6/11/2005 | COM | Loaiza | Promoted to active roster | | | Before |
| 6/11/2005 | COM | Patterson | Demoted to reserve roster | | | Before |
| 6/11/2005 | COM | Ponson | Promoted to active roster | | | Before |
| 6/11/2005 | COM | Wolf | Demoted to reserve roster | | | Before |
| 6/11/2005 | COM | Wolf | Promoted to active roster | | | Before |
| 6/11/2005 | FOR | Cerda | Demoted to reserve roster | | | Before |
| 6/11/2005 | FOR | Gotay | Demoted to reserve roster | | | Before |
| 6/11/2005 | FOR | Hawpe | Promoted to active roster | | | Before |
| 6/11/2005 | FOR | McPherson | Demoted to reserve roster | | | Before |
| 6/11/2005 | FOR | McPherson | Promoted to active roster | | | Before |
| 6/11/2005 | FOR | Neal | Promoted to active roster | | | Before |
| 6/11/2005 | FOR | Sullivan | Promoted to active roster | | | Before |
| 6/11/2005 | FOR | Sweeney | Promoted to active roster | | | Before |
| 6/11/2005 | FOR | Walker | Demoted to reserve roster | | | Before |
| 6/11/2005 | FOR | Witasick | Demoted to reserve roster | | | Before |
| 6/11/2005 | HEN | Bradford | Released | | | Before |
| 6/11/2005 | HEN | Pratt | Signed | | | Before |
| 6/11/2005 | HSX | Colome | Promoted to active roster | | | Before |
| 6/11/2005 | HSX | Turnbow | Demoted to reserve roster | | | Before |
| 6/11/2005 | HYS | Benoit | Demoted to reserve roster | | | Before |
| 6/11/2005 | HYS | Francis | Promoted to active roster | | | Before |
| 6/11/2005 | HYS | Franklin | Demoted to reserve roster | | | Before |
| 6/11/2005 | HYS | Greene | Demoted to reserve roster | | | Before |
| 6/11/2005 | HYS | Grimsley | Demoted to reserve roster | | | Before |
| 6/11/2005 | HYS | Lopez | Demoted to reserve roster | | | Before |
| 6/11/2005 | HYS | Miller | Promoted to active roster | | | Before |
| 6/11/2005 | HYS | Molina,J | Promoted to active roster | | | Before |
| 6/11/2005 | HYS | Reitsma | Promoted to active roster | | | Before |
| 6/11/2005 | HYS | Tankersley | Promoted to active roster | | | Before |
| 6/11/2005 | HYS | Wilson | Demoted to reserve roster | | | Before |
| 6/11/2005 | HYS | Woodward | Promoted to active roster | | | Before |
| 6/11/2005 | SLG | Griffey | Promoted to active roster | | | Before |
| 6/11/2005 | SLG | Hancock | Demoted to reserve roster | | | Before |
| 6/11/2005 | SLG | Restovich | Demoted to reserve roster | | | Before |
| 6/11/2005 | SLG | Vogelsong | Promoted to active roster | | | Before |
| 6/11/2005 | SYN | German | Demoted to reserve roster | | | Before |
| 6/11/2005 | SYN | Larkin | Promoted to active roster | | | Before |
| 6/11/2005 | SYN | Ludwick | Demoted to reserve roster | | | Before |
| 6/11/2005 | SYN | Mauer | Demoted to reserve roster | | | Before |
| 6/11/2005 | SYN | Rivera | Promoted to active roster | | | Before |
| 6/11/2005 | SYN | Snow | Demoted to reserve roster | | | Before |
| 6/11/2005 | SYN | Tsao | Promoted to active roster | | | Before |
| 6/11/2005 | SYN | Valentin | Promoted to active roster | | | Before |
| 6/16/2005 | COM | Armas | Demoted to reserve roster | | | Before |
| 6/16/2005 | COM | Cota | Promoted to active roster | | | Before |
| 6/16/2005 | COM | Dreifort | Demoted to reserve roster | | | Before |
| 6/16/2005 | COM | Edmonds | Demoted to reserve roster | | | Before |
| 6/16/2005 | COM | Elarton | Promoted to active roster | | | Before |
| 6/16/2005 | COM | Gross | Promoted to active roster | | | Before |
| 6/16/2005 | COM | Posada | Demoted to reserve roster | | | Before |
| 6/16/2005 | COM | Ramirez | Demoted to reserve roster | | | Before |
| 6/16/2005 | COM | Snell | Promoted to active roster | | | Before |
| 6/16/2005 | COM | Swisher | Promoted to active roster | | | Before |
| 6/18/2005 | BLU | Farnsworth | Promoted to active roster | | | Before |
| 6/18/2005 | BLU | Randolph | Demoted to reserve roster | | | Before |
| 6/18/2005 | BST | Beltran,F | Demoted to reserve roster | | | Before |
| 6/18/2005 | BST | Colon | Demoted to reserve roster | | | Before |
| 6/18/2005 | BST | Cotts | Promoted to active roster | | | Before |
| 6/18/2005 | BST | Gload | Promoted to active roster | | | Before |
| 6/18/2005 | BST | Jordan | Demoted to reserve roster | | | Before |
| 6/18/2005 | BST | Miller | Promoted to active roster | | | Before |
| 6/18/2005 | BST | Saenz | Promoted to active roster | | | Before |
| 6/18/2005 | BST | Schoeneweis | Demoted to reserve roster | | | Before |
| 6/18/2005 | FOR | Cerda | Promoted to active roster | | | Before |
| 6/18/2005 | FOR | McPherson | Demoted to reserve roster | | | Before |
| 6/18/2005 | FOR | Neal | Demoted to reserve roster | | | Before |
| 6/18/2005 | FOR | Neal | Promoted to active roster | | | Before |
| 6/18/2005 | FOR | Ojeda | Promoted to active roster | | | Before |
| 6/18/2005 | FOR | Sullivan | Demoted to reserve roster | | | Before |
| 6/18/2005 | FOR | Torres | Demoted to reserve roster | | | Before |
| 6/18/2005 | FOR | Witasick | Promoted to active roster | | | Before |
| 6/18/2005 | HEG | Brown | Demoted to reserve roster | | | Before |
| 6/18/2005 | HEG | Chavez | Demoted to reserve roster | | | Before |
| 6/18/2005 | HEG | Chavez | Promoted to active roster | | | Before |
| 6/18/2005 | HEG | Gonzalez | Demoted to reserve roster | | | Before |
| 6/18/2005 | HEG | Gonzalez | Promoted to active roster | | | Before |
| 6/18/2005 | HEG | Harang | Promoted to active roster | | | Before |
| 6/18/2005 | HEG | Thome | Demoted to reserve roster | | | Before |
| 6/18/2005 | HEG | Thome | Promoted to active roster | | | Before |
| 6/18/2005 | HEG | Ward | Demoted to reserve roster | | | Before |
| 6/18/2005 | HEG | Ward | Promoted to active roster | | | Before |
| 6/18/2005 | HSX | Field | Signed | | | Before |
| 6/18/2005 | HSX | Liriano | Released | | | Before |
| 6/18/2005 | HYS | Greene | Promoted to active roster | | | Before |
| 6/18/2005 | HYS | Lopez | Promoted to active roster | | | Before |
| 6/18/2005 | HYS | Peavy | Demoted to reserve roster | | | Before |
| 6/18/2005 | HYS | Ross | Demoted to reserve roster | | | Before |
| 6/18/2005 | HYS | Wilson | Promoted to active roster | | | Before |
| 6/18/2005 | HYS | Woodward | Demoted to reserve roster | | | Before |
| 6/18/2005 | SLG | Alomar,R | Demoted to reserve roster | | | Before |
| 6/18/2005 | SLG | Donnelly | Promoted to active roster | | | Before |
| 6/18/2005 | SLG | Hancock | Promoted to active roster | | | Before |
| 6/18/2005 | SLG | Vogelsong | Demoted to reserve roster | | | Before |
| 6/18/2005 | SYN | German | Promoted to active roster | | | Before |
| 6/18/2005 | SYN | Larkin | Demoted to reserve roster | | | Before |
| 6/18/2005 | SYN | Mauer | Promoted to active roster | | | Before |
| 6/18/2005 | SYN | Snow | Promoted to active roster | | | Before |
| 6/18/2005 | SYN | Valentin | Demoted to reserve roster | | | Before |
| 6/24/2005 | ANR | Bell | Promoted to active roster | | | Before |
| 6/24/2005 | ANR | Calero | Demoted to reserve roster | | | Before |
| 6/24/2005 | ANR | Germano | Promoted to active roster | | | Before |
| 6/24/2005 | ANR | Jackson | Demoted to reserve roster | | | Before |
| 6/24/2005 | ANR | Martinez | Demoted to reserve roster | | | Before |
| 6/24/2005 | ANR | Sexson | Promoted to active roster | | | Before |
| 6/24/2005 | BOU | Crain | Demoted to reserve roster | | | Before |
| 6/24/2005 | BOU | League | Promoted to active roster | | | Before |
| 6/24/2005 | COM | Armas | Demoted to reserve roster | | | Before |
| 6/24/2005 | COM | Brazoban | Promoted to active roster | | | Before |
| 6/24/2005 | FOR | Cerda | Demoted to reserve roster | | | Before |
| 6/24/2005 | FOR | Hawpe | Demoted to reserve roster | | | Before |
| 6/24/2005 | FOR | Ransom | Promoted to active roster | | | Before |
| 6/24/2005 | FOR | Sullivan | Promoted to active roster | | | Before |
| 6/24/2005 | FOR | Torres | Promoted to active roster | | | Before |
| 6/24/2005 | FOR | Witasick | Demoted to reserve roster | | | Before |
| 6/24/2005 | HEG | Hammond | Demoted to reserve roster | | | Before |
| 6/24/2005 | HEG | Millwood | Promoted to active roster | | | Before |
| 6/24/2005 | HEN | Pratt | Demoted to reserve roster | | | Before |
| 6/24/2005 | HEN | Wright | Promoted to active roster | | | Before |
| 6/24/2005 | HYS | Carrasco | Promoted to active roster | | | Before |
| 6/24/2005 | HYS | Cedeno | Promoted to active roster | | | Before |
| 6/24/2005 | HYS | Francis | Demoted to reserve roster | | | Before |
| 6/24/2005 | HYS | Greene | Promoted to active roster | | | Before |
| 6/24/2005 | HYS | Heilman | Promoted to active roster | | | Before |
| 6/24/2005 | HYS | Koplove | Demoted to reserve roster | | | Before |
| 6/24/2005 | HYS | Lopez | Promoted to active roster | | | Before |
| 6/24/2005 | HYS | Molina,J | Demoted to reserve roster | | | Before |
| 6/24/2005 | HYS | Nix | Demoted to reserve roster | | | Before |
| 6/24/2005 | HYS | Peavy | Demoted to reserve roster | | | Before |
| 6/24/2005 | HYS | Wilson | Promoted to active roster | | | Before |
| 6/24/2005 | HYS | Woodward | Demoted to reserve roster | | | Before |
| 6/24/2005 | SLG | Hancock | Demoted to reserve roster | | | Before |
| 6/24/2005 | SLG | Vogelsong | Promoted to active roster | | | Before |
| 6/24/2005 | SYN | German | Demoted to reserve roster | | | Before |
| 6/24/2005 | SYN | Mauer | Demoted to reserve roster | | | Before |
| 6/24/2005 | SYN | Valentin | Promoted to active roster | | | Before |
| 6/29/2005 | ANR | Martinez | Promoted to active roster | | | Before |
| 6/29/2005 | ANR | Sexson | Demoted to reserve roster | | | Before |
| 6/29/2005 | COM | Brazoban | Demoted to reserve roster | | | Before |
| 6/29/2005 | COM | Gross | Promoted to active roster | | | Before |
| 7/1/2005 | BLU | Floyd | Promoted to active roster | | | Before |
| 7/1/2005 | BLU | Jennings | Demoted to reserve roster | | | Before |
| 7/1/2005 | BLU | Mueller | Promoted to active roster | | | Before |
| 7/1/2005 | BLU | Polanco | Demoted to reserve roster | | | Before |
| 7/1/2005 | BOU | Ainsworth | Demoted to reserve roster | | | Before |
| 7/1/2005 | BOU | Ankiel | Promoted to active roster | | | Before |
| 7/1/2005 | BOU | Garcia | Demoted to reserve roster | | | Before |
| 7/1/2005 | BST | Cotts | Demoted to reserve roster | | | Before |
| 7/1/2005 | BST | Hendrickson | Promoted to active roster | | | Before |
| 7/1/2005 | BST | Martinez,A | Promoted to active roster | | | Before |
| 7/1/2005 | BST | Saenz | Demoted to reserve roster | | | Before |
| 7/1/2005 | FOR | Cerda | Promoted to active roster | | | Before |
| 7/1/2005 | FOR | McPherson | Promoted to active roster | | | Before |
| 7/1/2005 | FOR | Neal | Demoted to reserve roster | | | Before |
| 7/1/2005 | FOR | Ojeda | Demoted to reserve roster | | | Before |
| 7/1/2005 | FOR | Ransom | Demoted to reserve roster | | | Before |
| 7/1/2005 | FOR | Walker | Promoted to active roster | | | Before |
| 7/1/2005 | FOR | Witasick | Promoted to active roster | | | Before |
| 7/1/2005 | FOR | Yan | Demoted to reserve roster | | | Before |
| 7/1/2005 | HSX | Putz | Demoted to reserve roster | | | Before |
| 7/1/2005 | HSX | Young,C | Promoted to active roster | | | Before |
| 7/1/2005 | HYS | Benoit | Promoted to active roster | | | Before |
| 7/1/2005 | HYS | Cedeno | Demoted to reserve roster | | | Before |
| 7/1/2005 | HYS | Franklin | Promoted to active roster | | | Before |
| 7/1/2005 | HYS | Heilman | Demoted to reserve roster | | | Before |
| 7/1/2005 | HYS | Koplove | Demoted to reserve roster | | | Before |
| 7/1/2005 | HYS | Koplove | Promoted to active roster | | | Before |
| 7/1/2005 | HYS | Miller | Demoted to reserve roster | | | Before |
| 7/1/2005 | HYS | Nix | Promoted to active roster | | | Before |
| 7/1/2005 | HYS | Peavy | Promoted to active roster | | | Before |
| 7/1/2005 | HYS | Tankersley | Demoted to reserve roster | | | Before |
| 7/1/2005 | SLG | Alomar,R | Released | | | Before |
| 7/1/2005 | SLG | Hunter | Demoted to reserve roster | | | Before |
| 7/1/2005 | SLG | Kroeger | Promoted to active roster | | | Before |
| 7/1/2005 | SLG | Towers | Signed | | | Before |
| 7/1/2005 | SLG | Vogelsong | Demoted to reserve roster | | | Before |
| 7/1/2005 | SYN | Larkin | Promoted to active roster | | | Before |
| 7/1/2005 | SYN | Mauer | Promoted to active roster | | | Before |
| 7/1/2005 | SYN | Tsao | Demoted to reserve roster | | | Before |
| 7/1/2005 | SYN | Valentin | Demoted to reserve roster | | | Before |
| 7/2/2005 | ANR | Piedra | Promoted to active roster | | | Before |
| 7/2/2005 | BST | Saenz | Promoted to active roster | | | Before |
| 7/2/2005 | HSX | Capellan | Promoted to active roster | | | Before |
| 7/4/2005 | HSX | Capellan | Demoted to reserve roster | | | Before |
| 7/5/2005 | HYS | Grimsley | Promoted to active roster | | | Before |
| 7/5/2005 | HYS | Woodward | Promoted to active roster | | | Before |
| 7/7/2005 | ANR | Branyan | Demoted to reserve roster | | | Before |
| 7/7/2005 | ANR | Keppinger | Promoted to active roster | | | Before |
| 7/7/2005 | ANR | Martinez | Demoted to reserve roster | | | Before |
| 7/7/2005 | ANR | Sexson | Promoted to active roster | | | Before |
| 7/7/2005 | BLU | Blanco | Demoted to reserve roster | | | Before |
| 7/7/2005 | BLU | Floyd | Demoted to reserve roster | | | Before |
| 7/7/2005 | BLU | Jennings | Promoted to active roster | | | Before |
| 7/7/2005 | BLU | Lopez,J | Demoted to reserve roster | | | Before |
| 7/7/2005 | BLU | Lopez,J | Promoted to active roster | | | Before |
| 7/7/2005 | BLU | Lopez,J | Promoted to active roster | | | Before |
| 7/7/2005 | BLU | Polanco | Promoted to active roster | | | Before |
| 7/7/2005 | BLU | Quinlan | Demoted to reserve roster | | | Before |
| 7/7/2005 | BOU | Ainsworth | Released | | | Before |
| 7/7/2005 | BOU | Ankiel | Released | | | Before |
| 7/7/2005 | BOU | Bradford | Signed | | | Before |
| 7/7/2005 | BOU | Dohmann | Released | | | Before |
| 7/7/2005 | BOU | Myers | Signed | | | Before |
| 7/7/2005 | BOU | Powell | Signed | | | Before |
| 7/7/2005 | FOR | Hawpe | Promoted to active roster | | | Before |
| 7/7/2005 | FOR | McPherson | Demoted to reserve roster | | | Before |
| 7/7/2005 | FOR | Ojeda | Promoted to active roster | | | Before |
| 7/7/2005 | FOR | Ransom | Promoted to active roster | | | Before |
| 7/7/2005 | FOR | Sullivan | Demoted to reserve roster | | | Before |
| 7/7/2005 | FOR | Sweeney | Demoted to reserve roster | | | Before |
| 7/7/2005 | FOR | Yan | Promoted to active roster | | | Before |
| 7/7/2005 | HEN | Cust | Released | | | Before |
| 7/7/2005 | HEN | Garcia,D | Promoted to active roster | | | Before |
| 7/7/2005 | HEN | Saenz | Signed | | | Before |
| 7/7/2005 | HEN | Saenz | Demoted to reserve roster | | | Before |
| 7/7/2005 | HEN | Thames | Demoted to reserve roster | | | Before |
| 7/7/2005 | HEN | Williamson | Promoted to active roster | | | Before |
| 7/7/2005 | HSX | Colome | Demoted to reserve roster | | | Before |
| 7/7/2005 | HSX | Nomo | Demoted to reserve roster | | | Before |
| 7/7/2005 | HSX | Putz | Promoted to active roster | | | Before |
| 7/7/2005 | HSX | Wagner | Promoted to active roster | | | Before |
| 7/7/2005 | HYS | Anderson | Demoted to reserve roster | | | Before |
| 7/7/2005 | HYS | Koplove | Promoted to active roster | | | Before |
| 7/7/2005 | HYS | Lopez | Demoted to reserve roster | | | Before |
| 7/7/2005 | HYS | Mecir | Demoted to reserve roster | | | Before |
| 7/7/2005 | HYS | Miller | Promoted to active roster | | | Before |
| 7/7/2005 | HYS | Molina,J | Promoted to active roster | | | Before |
| 7/7/2005 | HYS | Nivar | Promoted to active roster | | | Before |
| 7/7/2005 | HYS | Peavy | Demoted to reserve roster | | | Before |
| 7/7/2005 | HYS | Perisho | Demoted to reserve roster | | | Before |
| 7/7/2005 | HYS | Ross | Demoted to reserve roster | | | Before |
| 7/7/2005 | SLG | Burrell | Demoted to reserve roster | | | Before |
| 7/7/2005 | SLG | Hunter | Promoted to active roster | | | Before |
| 7/7/2005 | SLG | Park | Demoted to reserve roster | | | Before |
| 7/7/2005 | SLG | Vogelsong | Promoted to active roster | | | Before |
| 7/7/2005 | SYN | Mauer | Demoted to reserve roster | | | Before |
| 7/7/2005 | SYN | Valentin | Promoted to active roster | | | Before |
| 7/8/2005 | FOR | Cabrera | Promoted to active roster | | | Before |
| 7/11/2005 | BST | Beltran,F | Promoted to active roster | | | Before |
| 7/11/2005 | FOR | Neal | Promoted to active roster | | | Before |
| 7/12/2005 | ANR | Kotchman | Promoted to active roster | | | Before |
| 7/12/2005 | ANR | Sexson | Demoted to reserve roster | | | Before |
| 7/14/2005 | BLU | Frasor | Demoted to reserve roster | | | Before |
| 7/14/2005 | BLU | Leicester | Promoted to active roster | | | Before |
| 7/14/2005 | BOU | Buck | Promoted to active roster | | | Before |
| 7/14/2005 | BOU | Claussen | Demoted to reserve roster | | | Before |
| 7/14/2005 | BOU | League | Demoted to reserve roster | | | Before |
| 7/14/2005 | BOU | LeCroy | Demoted to reserve roster | | | Before |
| 7/14/2005 | BOU | Wheeler | Demoted to reserve roster | | | Before |
| 7/14/2005 | BST | Anderson | Demoted to reserve roster | | | Before |
| 7/14/2005 | BST | Clark | Promoted to active roster | | | Before |
| 7/14/2005 | BST | Francisco | Demoted to reserve roster | | | Before |
| 7/14/2005 | BST | Guardado | Demoted to reserve roster | | | Before |
| 7/14/2005 | COM | Elarton | Promoted to active roster | | | Before |
| 7/14/2005 | COM | Gryboski | Demoted to reserve roster | | | Before |
| 7/14/2005 | COM | Patterson | Promoted to active roster | | | Before |
| 7/14/2005 | COM | Wolf | Demoted to reserve roster | | | Before |
| 7/14/2005 | FOR | Bruntlett | Signed | | | Before |
| 7/14/2005 | FOR | Bruntlett | Demoted to reserve roster | | | Before |
| 7/14/2005 | FOR | Cabrera | Demoted to reserve roster | | | Before |
| 7/14/2005 | FOR | Cabrera | Promoted to active roster | | | Before |
| 7/14/2005 | FOR | Cerda | Demoted to reserve roster | | | Before |
| 7/14/2005 | FOR | Ohka | Promoted to active roster | | | Before |
| 7/14/2005 | FOR | Pettitte | Demoted to reserve roster | | | Before |
| 7/14/2005 | FOR | Ransom | Released | | | Before |
| 7/14/2005 | FOR | Sullivan | Demoted to reserve roster | | | Before |
| 7/14/2005 | FOR | Sullivan | Promoted to active roster | | | Before |
| 7/14/2005 | FOR | Sweeney | Promoted to active roster | | | Before |
| 7/14/2005 | FOR | Walker | Demoted to reserve roster | | | Before |
| 7/14/2005 | FOR | Witasick | Demoted to reserve roster | | | Before |
| 7/14/2005 | HEN | Thames | Promoted to active roster | | | Before |
| 7/14/2005 | HEN | Williamson | Demoted to reserve roster | | | Before |
| 7/14/2005 | HSX | Broussard | Demoted to reserve roster | | | Before |
| 7/14/2005 | HSX | Howard | Promoted to active roster | | | Before |
| 7/16/2005 | BLU | Delgado | Placed on disabled list | | 7/16/2005 | Before |
| 7/16/2005 | BLU | Quinlan | Promoted to active roster | | | Before |
| 7/16/2005 | COM | Wolf | Promoted to active roster | | | Before |
| 7/19/2005 | ANR | Branyan | Promoted to active roster | | | Before |
| 7/19/2005 | ANR | Keppinger | Demoted to reserve roster | | | Before |
| 7/19/2005 | ANR | Kotchman | Demoted to reserve roster | | | Before |
| 7/19/2005 | ANR | Martinez | Promoted to active roster | | | Before |
| 7/20/2005 | BLU | Delgado | Activated from disabled list | | | Before |
| 7/20/2005 | BLU | Quinlan | Demoted to reserve roster | | | Before |
| 7/20/2005 | BST | Anderson | Promoted to active roster | | | Before |
| 7/20/2005 | BST | Beltran,F | Demoted to reserve roster | | | Before |
| 7/20/2005 | BST | Clark | Demoted to reserve roster | | | Before |
| 7/20/2005 | BST | Colon | Promoted to active roster | | | Before |
| 7/20/2005 | BST | Franco | Promoted to active roster | | | Before |
| 7/20/2005 | BST | Guardado | Promoted to active roster | | | Before |
| 7/20/2005 | BST | Martinez,A | Demoted to reserve roster | | | Before |
| 7/20/2005 | BST | Saenz | Demoted to reserve roster | | | Before |
| 7/20/2005 | COM | Edmonds | Demoted to reserve roster | | | Before |
| 7/20/2005 | COM | Swisher | Promoted to active roster | | | Before |
| 7/20/2005 | COM | Wolf | Demoted to reserve roster | | | Before |
| 7/20/2005 | FOR | Bruntlett | Promoted to active roster | | | Before |
| 7/20/2005 | FOR | Foulke | Demoted to reserve roster | | | Before |
| 7/20/2005 | FOR | Ojeda | Demoted to reserve roster | | | Before |
| 7/20/2005 | FOR | Sullivan | Promoted to active roster | | | Before |
| 7/20/2005 | HEN | Saenz | Promoted to active roster | | | Before |
| 7/20/2005 | HEN | Thames | Demoted to reserve roster | | | Before |
| 7/20/2005 | HEN | Williams | Demoted to reserve roster | | | Before |
| 7/20/2005 | HSX | Broussard | Promoted to active roster | | | Before |
| 7/20/2005 | HSX | Colome | Promoted to active roster | | | Before |
| 7/20/2005 | HSX | Howard | Demoted to reserve roster | | | Before |
| 7/20/2005 | HSX | Padilla | Demoted to reserve roster | | | Before |
| 7/20/2005 | HSX | Phelps | Demoted to reserve roster | | | Before |
| 7/20/2005 | HSX | Ramirez | Promoted to active roster | | | Before |
| 7/20/2005 | HYS | Anderson | Promoted to active roster | | | Before |
| 7/20/2005 | HYS | Carrasco | Demoted to reserve roster | | | Before |
| 7/20/2005 | HYS | Greene | Demoted to reserve roster | | | Before |
| 7/20/2005 | HYS | Hill | Demoted to reserve roster | | | Before |
| 7/20/2005 | HYS | Koplove | Demoted to reserve roster | | | Before |
| 7/20/2005 | HYS | Mecir | Promoted to active roster | | | Before |
| 7/20/2005 | HYS | Miller | Demoted to reserve roster | | | Before |
| 7/20/2005 | HYS | Peavy | Promoted to active roster | | | Before |
| 7/20/2005 | HYS | Perisho | Promoted to active roster | | | Before |
| 7/20/2005 | HYS | Ross | Promoted to active roster | | | Before |
| 7/20/2005 | SLG | Betemit | Promoted to active roster | | | Before |
| 7/20/2005 | SLG | Knotts | Signed | | | Before |
| 7/20/2005 | SLG | Prior | Demoted to reserve roster | | | Before |
| 7/20/2005 | SLG | Salmon | Demoted to reserve roster | | | Before |
| 7/20/2005 | SLG | Torcato | Released | | | Before |
| 7/22/2005 | COM | Snell | Promoted to active roster | | | Before |
| 7/24/2005 | BLU | Polanco | Placed on disabled list | | 7/24/2005 | Before |
| 7/24/2005 | BLU | Quinlan | Promoted to active roster | | | Before |
| 7/24/2005 | BLU | Robinson | Promoted to active roster | | | Before |
| 7/24/2005 | BLU | Womack | Placed on disabled list | | 7/24/2005 | Before |
| 7/24/2005 | SYN | Ludwick | Promoted to active roster | | | Before |
| 7/24/2005 | SYN | Mauer | Promoted to active roster | | | Before |
| 7/25/2005 | SYN | Ludwick | Demoted to reserve roster | | | Before |
| 7/25/2005 | SYN | Mauer | Demoted to reserve roster | | | Before |
| 7/26/2005 | BLU | Polanco | Activated from disabled list | | | Before |
| 7/26/2005 | BLU | Womack | Activated from disabled list | | | Before |
| 7/27/2005 | ANR | Kieschnick | Demoted to reserve roster | | | Before |
| 7/27/2005 | ANR | Kotchman | Promoted to active roster | | | Before |
| 7/27/2005 | ANR | Martinez | Demoted to reserve roster | | | Before |
| 7/27/2005 | BLU | Diaz | Demoted to reserve roster | | | Before |
| 7/27/2005 | BLU | Farnsworth | Demoted to reserve roster | | | Before |
| 7/27/2005 | BLU | Frasor | Promoted to active roster | | | Before |
| 7/27/2005 | BLU | Robinson | Demoted to reserve roster | | | Before |
| 7/27/2005 | BOU | Kearns | Demoted to reserve roster | | | Before |
| 7/27/2005 | BOU | Pena | Promoted to active roster | | | Before |
| 7/27/2005 | BOU | Spivey | Promoted to active roster | | | Before |
| 7/27/2005 | BST | Anderson | Demoted to reserve roster | | | Before |
| 7/27/2005 | BST | Cabrera | Demoted to reserve roster | | | Before |
| 7/27/2005 | BST | Clark | Promoted to active roster | | | Before |
| 7/27/2005 | BST | Guardado | Demoted to reserve roster | | | Before |
| 7/27/2005 | BST | Saenz | Promoted to active roster | | | Before |
| 7/27/2005 | BST | Wood | Promoted to active roster | | | Before |
| 7/27/2005 | COM | Armas | Promoted to active roster | | | Before |
| 7/27/2005 | COM | Edmonds | Promoted to active roster | | | Before |
| 7/27/2005 | COM | Elarton | Demoted to reserve roster | | | Before |
| 7/27/2005 | COM | Snell | Demoted to reserve roster | | | Before |
| 7/27/2005 | COM | Swisher | Demoted to reserve roster | | | Before |
| 7/27/2005 | COM | Wolf | Demoted to reserve roster | | | Before |
| 7/27/2005 | COM | Wolf | Promoted to active roster | | | Before |
| 7/27/2005 | FOR | Bruntlett | Demoted to reserve roster | | | Before |
| 7/27/2005 | FOR | Cabrera | Demoted to reserve roster | | | Before |
| 7/27/2005 | FOR | Cerda | Promoted to active roster | | | Before |
| 7/27/2005 | FOR | Foulke | Promoted to active roster | | | Before |
| 7/27/2005 | FOR | Hawpe | Demoted to reserve roster | | | Before |
| 7/27/2005 | FOR | Hawpe | Promoted to active roster | | | Before |
| 7/27/2005 | FOR | Mateo | Signed | | | Before |
| 7/27/2005 | FOR | Neal | Demoted to reserve roster | | | Before |
| 7/27/2005 | FOR | Ohka | Demoted to reserve roster | | | Before |
| 7/27/2005 | FOR | Ojeda | Released | | | Before |
| 7/27/2005 | FOR | Pettitte | Promoted to active roster | | | Before |
| 7/27/2005 | FOR | Sullivan | Demoted to reserve roster | | | Before |
| 7/27/2005 | FOR | Sweeney | Demoted to reserve roster | | | Before |
| 7/27/2005 | FOR | Walker | Promoted to active roster | | | Before |
| 7/27/2005 | FOR | Witasick | Promoted to active roster | | | Before |
| 7/27/2005 | HEG | Maddux | Demoted to reserve roster | | | Before |
| 7/27/2005 | HEG | Wright | Promoted to active roster | | | Before |
| 7/27/2005 | HEN | Davis | Promoted to active roster | | | Before |
| 7/27/2005 | HEN | Garcia,D | Demoted to reserve roster | | | Before |
| 7/27/2005 | HEN | Glover | Signed | | | Before |
| 7/27/2005 | HEN | Glover | Demoted to reserve roster | | | Before |
| 7/27/2005 | HEN | Karsay | Released | | | Before |
| 7/27/2005 | HEN | Mondesi | Released | | | Before |
| 7/27/2005 | HEN | Nelson | Signed | | | Before |
| 7/27/2005 | HEN | Nelson | Demoted to reserve roster | | | Before |
| 7/27/2005 | HEN | Redmond | Demoted to reserve roster | | | Before |
| 7/27/2005 | HEN | Saenz | Released | | | Before |
| 7/27/2005 | HEN | Saenz | Demoted to reserve roster | | | Before |
| 7/27/2005 | HEN | Sanchez | Promoted to active roster | | | Before |
| 7/27/2005 | HEN | Stanford | Signed | | | Before |
| 7/27/2005 | HEN | Stanford | Demoted to reserve roster | | | Before |
| 7/27/2005 | HEN | Williams | Promoted to active roster | | | Before |
| 7/27/2005 | HSX | Broussard | Demoted to reserve roster | | | Before |
| 7/27/2005 | HSX | Colome | Demoted to reserve roster | | | Before |
| 7/27/2005 | HSX | Colome | Promoted to active roster | | | Before |
| 7/27/2005 | HSX | Colome | Demoted to reserve roster | | | Before |
| 7/27/2005 | HSX | Howard | Promoted to active roster | | | Before |
| 7/27/2005 | HSX | Loe | Promoted to active roster | | | Before |
| 7/27/2005 | HSX | Riley | Promoted to active roster | | | Before |
| 7/27/2005 | HSX | Young,C | Demoted to reserve roster | | | Before |
| 7/27/2005 | SLG | Betemit | Demoted to reserve roster | | | Before |
| 7/27/2005 | SLG | Burrell | Promoted to active roster | | | Before |
| 7/27/2005 | SLG | Eischen | Promoted to active roster | | | Before |
| 7/27/2005 | SLG | Hasegawa | Demoted to reserve roster | | | Before |
| 7/27/2005 | SLG | Helms | Demoted to reserve roster | | | Before |
| 7/27/2005 | SLG | Salmon | Promoted to active roster | | | Before |
| 7/27/2005 | SLG | Wickman | Demoted to reserve roster | | | Before |
| 7/27/2005 | SLG | Wickman | Promoted to active roster | | | Before |
| 7/28/2005 | HSX | Graffanino | Promoted to active roster | | | Before |
| 8/1/2005 | ANR | Johnson | Demoted to reserve roster | | | Before |
| 8/1/2005 | ANR | Kotchman | Demoted to reserve roster | | | Before |
| 8/1/2005 | ANR | Martinez | Promoted to active roster | | | Before |
| 8/1/2005 | ANR | Quintero | Promoted to active roster | | | Before |
| 8/1/2005 | HEN | Glover | Signed | | | Before |
| 8/1/2005 | HEN | Karsay | Released | | | Before |
| 8/1/2005 | HEN | Mondesi | Released | | | Before |
| 8/1/2005 | HEN | Nelson | Signed | | | Before |
| 8/1/2005 | HEN | Saenz | Released | | | Before |
| 8/1/2005 | HEN | Stanford | Signed | | | Before |
| 8/2/2005 | BOU | Burnett | Demoted to reserve roster | | | Before |
| 8/2/2005 | BOU | Dickey | Signed | | | Before |
| 8/2/2005 | BOU | Nady | Demoted to reserve roster | | | Before |
| 8/2/2005 | BOU | Nady | Promoted to active roster | | | Before |
| 8/2/2005 | BOU | Oliver | Signed | | | Before |
| 8/2/2005 | BOU | Rauch | Released | | | Before |
| 8/2/2005 | BOU | Spivey | Released | | | Before |
| 8/2/2005 | BST | Anderson | Promoted to active roster | | | Before |
| 8/2/2005 | BST | Beltran,F | Promoted to active roster | | | Before |
| 8/2/2005 | BST | Colon | Demoted to reserve roster | | | Before |
| 8/2/2005 | BST | Hendrickson | Demoted to reserve roster | | | Before |
| 8/2/2005 | BST | Saenz | Demoted to reserve roster | | | Before |
| 8/2/2005 | BST | Schoeneweis | Promoted to active roster | | | Before |
| 8/2/2005 | COM | Armas | Demoted to reserve roster | | | Before |
| 8/2/2005 | COM | Elarton | Promoted to active roster | | | Before |
| 8/2/2005 | COM | Melhuse | Released | | | Before |
| 8/2/2005 | COM | Stinnett | Signed | | | Before |
| 8/2/2005 | FOR | Ohka | Promoted to active roster | | | Before |
| 8/2/2005 | FOR | Pettitte | Demoted to reserve roster | | | Before |
| 8/2/2005 | FOR | Rincon | Demoted to reserve roster | | | Before |
| 8/2/2005 | FOR | Sullivan | Promoted to active roster | | | Before |
| 8/2/2005 | FOR | Sweeney | Promoted to active roster | | | Before |
| 8/2/2005 | FOR | Walker | Demoted to reserve roster | | | Before |
| 8/2/2005 | HEG | Garciaparra | Demoted to reserve roster | | | Before |
| 8/2/2005 | HEG | Gonzalez | Promoted to active roster | | | Before |
| 8/2/2005 | HEG | Maddux | Promoted to active roster | | | Before |
| 8/2/2005 | HEG | Mirabelli | Demoted to reserve roster | | | Before |
| 8/2/2005 | HEG | Molina | Promoted to active roster | | | Before |
| 8/2/2005 | HEG | Pierzynski | Demoted to reserve roster | | | Before |
| 8/2/2005 | HEG | Rusch | Demoted to reserve roster | | | Before |
| 8/2/2005 | HEG | Santiago | Promoted to active roster | | | Before |
| 8/2/2005 | HEG | Thome | Demoted to reserve roster | | | Before |
| 8/2/2005 | HEG | Ward | Promoted to active roster | | | Before |
| 8/2/2005 | HEN | Stanford | Promoted to active roster | | | Before |
| 8/2/2005 | HEN | Tomko | Demoted to reserve roster | | | Before |
| 8/2/2005 | HSX | Broussard | Promoted to active roster | | | Before |
| 8/2/2005 | HSX | Colome | Promoted to active roster | | | Before |
| 8/2/2005 | HSX | Graffanino | Demoted to reserve roster | | | Before |
| 8/2/2005 | HSX | Howard | Demoted to reserve roster | | | Before |
| 8/2/2005 | HSX | Loe | Demoted to reserve roster | | | Before |
| 8/2/2005 | HYS | Bedard | Demoted to reserve roster | | | Before |
| 8/2/2005 | HYS | Benoit | Demoted to reserve roster | | | Before |
| 8/2/2005 | HYS | Carrasco | Promoted to active roster | | | Before |
| 8/2/2005 | HYS | Cedeno | Promoted to active roster | | | Before |
| 8/2/2005 | HYS | Francis | Demoted to reserve roster | | | Before |
| 8/2/2005 | HYS | Francis | Promoted to active roster | | | Before |
| 8/2/2005 | HYS | Greene | Promoted to active roster | | | Before |
| 8/2/2005 | HYS | Grimsley | Demoted to reserve roster | | | Before |
| 8/2/2005 | HYS | Heilman | Promoted to active roster | | | Before |
| 8/2/2005 | HYS | Lopez | Promoted to active roster | | | Before |
| 8/2/2005 | HYS | Miller | Promoted to active roster | | | Before |
| 8/2/2005 | HYS | Nivar | Demoted to reserve roster | | | Before |
| 8/2/2005 | HYS | Perez | Demoted to reserve roster | | | Before |
| 8/2/2005 | HYS | Perez | Promoted to active roster | | | Before |
| 8/2/2005 | HYS | Ross | Demoted to reserve roster | | | Before |
| 8/2/2005 | HYS | Woodward | Demoted to reserve roster | | | Before |
| 8/2/2005 | SLG | Betemit | Promoted to active roster | | | Before |
| 8/6/2005 | HEN | Tomko | Promoted to active roster | | | Before |
| 8/6/2005 | HEN | Williams | Placed on disabled list | | 8/2/2005 | Before |
| 8/7/2005 | SLG | Kroeger | Demoted to reserve roster | | | Before |
| 8/8/2005 | HEN | Williams | Activated from disabled list | | | Before |
| 8/9/2005 | BOU | Nady | Demoted to reserve roster | | | Before |
| 8/9/2005 | BST | Colon | Promoted to active roster | | | Before |
| 8/9/2005 | BST | Hendrickson | Promoted to active roster | | | Before |
| 8/9/2005 | BST | Mussina | Demoted to reserve roster | | | Before |
| 8/9/2005 | BST | Saenz | Promoted to active roster | | | Before |
| 8/9/2005 | BST | Villone | Demoted to reserve roster | | | Before |
| 8/9/2005 | BST | Vizcaino | Demoted to reserve roster | | | Before |
| 8/9/2005 | COM | Fossum | Demoted to reserve roster | | | Before |
| 8/9/2005 | COM | Wolf | Promoted to active roster | | | Before |
| 8/9/2005 | FOR | Alvarez | Signed | | | Before |
| 8/9/2005 | FOR | Bruntlett | Promoted to active roster | | | Before |
| 8/9/2005 | FOR | Cerda | Demoted to reserve roster | | | Before |
| 8/9/2005 | FOR | Cerda | Promoted to active roster | | | Before |
| 8/9/2005 | FOR | Hawpe | Demoted to reserve roster | | | Before |
| 8/9/2005 | FOR | Hawpe | Promoted to active roster | | | Before |
| 8/9/2005 | FOR | Hawpe | Demoted to reserve roster | | | Before |
| 8/9/2005 | FOR | Magruder | Released | | | Before |
| 8/9/2005 | FOR | Mateo | Demoted to reserve roster | | | Before |
| 8/9/2005 | FOR | Mateo | Promoted to active roster | | | Before |
| 8/9/2005 | FOR | Neal | Demoted to reserve roster | | | Before |
| 8/9/2005 | FOR | Neal | Promoted to active roster | | | Before |
| 8/9/2005 | FOR | Rincon | Promoted to active roster | | | Before |
| 8/9/2005 | FOR | Sullivan | Demoted to reserve roster | | | Before |
| 8/9/2005 | FOR | Sweeney | Demoted to reserve roster | | | Before |
| 8/9/2005 | FOR | Walker | Promoted to active roster | | | Before |
| 8/9/2005 | FOR | Witasick | Demoted to reserve roster | | | Before |
| 8/9/2005 | FOR | Witasick | Promoted to active roster | | | Before |
| 8/9/2005 | HEG | Carrara | Demoted to reserve roster | | | Before |
| 8/9/2005 | HEG | Hammond | Promoted to active roster | | | Before |
| 8/9/2005 | HEN | Davis | Demoted to reserve roster | | | Before |
| 8/9/2005 | HEN | Garcia,D | Promoted to active roster | | | Before |
| 8/9/2005 | HEN | Hernandez | Demoted to reserve roster | | | Before |
| 8/9/2005 | HEN | Redmond | Promoted to active roster | | | Before |
| 8/9/2005 | HEN | Rhodes | Demoted to reserve roster | | | Before |
| 8/9/2005 | HSX | Brito | Signed | | | Before |
| 8/9/2005 | HSX | Colome | Demoted to reserve roster | | | Before |
| 8/9/2005 | HSX | Colome | Promoted to active roster | | | Before |
| 8/9/2005 | HSX | Inge | Demoted to reserve roster | | | Before |
| 8/9/2005 | HSX | Nomo | Released | | | Before |
| 8/9/2005 | HSX | Turnbow | Promoted to active roster | | | Before |
| 8/9/2005 | HSX | Wagner | Demoted to reserve roster | | | Before |
| 8/9/2005 | HYS | Carrasco | Demoted to reserve roster | | | Before |
| 8/9/2005 | HYS | Grimsley | Promoted to active roster | | | Before |
| 8/9/2005 | HYS | Koplove | Promoted to active roster | | | Before |
| 8/9/2005 | HYS | Lopez | Demoted to reserve roster | | | Before |
| 8/9/2005 | HYS | Mecir | Demoted to reserve roster | | | Before |
| 8/9/2005 | HYS | Molina,J | Demoted to reserve roster | | | Before |
| 8/9/2005 | HYS | Ross | Promoted to active roster | | | Before |
| 8/9/2005 | HYS | Woodward | Promoted to active roster | | | Before |
| 8/11/2005 | BOU | LeCroy | Promoted to active roster | | | Before |
| 8/14/2005 | FOR | Bruntlett | Demoted to reserve roster | | | Before |
| 8/14/2005 | FOR | Cerda | Promoted to active roster | | | Before |
| 8/14/2005 | FOR | Mateo | Promoted to active roster | | | Before |
| 8/14/2005 | FOR | Ohka | Demoted to reserve roster | | | Before |
| 8/14/2005 | FOR | Pettitte | Promoted to active roster | | | Before |
| 8/14/2005 | FOR | Sullivan | Demoted to reserve roster | | | Before |
| 8/14/2005 | FOR | Sweeney | Demoted to reserve roster | | | Before |
| 8/14/2005 | FOR | Sweeney | Promoted to active roster | | | Before |
| 8/15/2005 | ANR | Gathright | Promoted to active roster | | | Before |
| 8/15/2005 | ANR | Kotchman | Promoted to active roster | | | Before |
| 8/15/2005 | ANR | Martinez | Demoted to reserve roster | | | Before |
| 8/15/2005 | ANR | Mohr | Demoted to reserve roster | | | Before |
| 8/15/2005 | BOU | Byrd | Released | | | Before |
| 8/15/2005 | BOU | Garcia | Released | | | Before |
| 8/15/2005 | BOU | Hentgen | Signed | | | Before |
| 8/15/2005 | BOU | Macias | Signed | | | Before |
| 8/15/2005 | BOU | Mulholland | Signed | | | Before |
| 8/15/2005 | BOU | SNELLING | Released | | | Before |
| 8/15/2005 | BOU | Wood | Demoted to reserve roster | | | Before |
| 8/15/2005 | BST | Colon | Demoted to reserve roster | | | Before |
| 8/15/2005 | BST | Villone | Promoted to active roster | | | Before |
| 8/15/2005 | COM | Brazoban | Promoted to active roster | | | Before |
| 8/15/2005 | COM | Dreifort | Demoted to reserve roster | | | Before |
| 8/15/2005 | HEG | Terrero | Demoted to reserve roster | | | Before |
| 8/15/2005 | HEG | Thome | Promoted to active roster | | | Before |
| 8/15/2005 | HEN | Davis | Promoted to active roster | | | Before |
| 8/15/2005 | HEN | Garcia,D | Demoted to reserve roster | | | Before |
| 8/15/2005 | HEN | Hernandez | Promoted to active roster | | | Before |
| 8/15/2005 | HEN | Redmond | Demoted to reserve roster | | | Before |
| 8/15/2005 | HEN | Stanford | Demoted to reserve roster | | | Before |
| 8/15/2005 | HEN | Williamson | Promoted to active roster | | | Before |
| 8/15/2005 | HSX | Graffanino | Demoted to reserve roster | | | Before |
| 8/15/2005 | HSX | Graffanino | Promoted to active roster | | | Before |
| 8/15/2005 | HSX | Hammock | Demoted to reserve roster | | | Before |
| 8/15/2005 | HSX | Hammock | Promoted to active roster | | | Before |
| 8/15/2005 | HSX | Inge | Promoted to active roster | | | Before |
| 8/15/2005 | HSX | Turnbow | Demoted to reserve roster | | | Before |
| 8/15/2005 | HSX | Wagner | Promoted to active roster | | | Before |
| 8/15/2005 | HSX | Wigginton | Demoted to reserve roster | | | Before |
| 8/15/2005 | SLG | Castro | Released | | | Before |
| 8/15/2005 | SLG | Nunez | Released | | | Before |
| 8/15/2005 | SLG | Nunez | Signed | | | Before |
| 8/15/2005 | SLG | Nunez | Signed | | | Before |
| 8/15/2005 | SYN | Bacsik | Signed | | | Before |
| 8/15/2005 | SYN | Day | Demoted to reserve roster | | | Before |
| 8/15/2005 | SYN | Fultz | Signed | | | Before |
| 8/15/2005 | SYN | Graves | Released | | | Before |
| 8/15/2005 | SYN | Lee | Released | | | Before |
| 8/19/2005 | BLU | Diaz | Promoted to active roster | | | Before |
| 8/20/2005 | ANR | Bell | Demoted to reserve roster | | | Before |
| 8/20/2005 | ANR | Gathright | Demoted to reserve roster | | | Before |
| 8/20/2005 | ANR | Kim | Promoted to active roster | | | Before |
| 8/20/2005 | ANR | Martinez | Promoted to active roster | | | Before |
| 8/20/2005 | BST | Cabrera | Promoted to active roster | | | Before |
| 8/20/2005 | BST | Saenz | Demoted to reserve roster | | | Before |
| 8/20/2005 | HSX | Inge | Demoted to reserve roster | | | Before |
| 8/20/2005 | HSX | Wigginton | Promoted to active roster | | | Before |
| 8/26/2005 | COM | Dreifort | Promoted to active roster | | | Before |
| 8/26/2005 | COM | Elarton | Demoted to reserve roster | | | Before |
| 8/26/2005 | COM | Giambi | Placed on disabled list | | 8/22/2005 | Before |
| 8/26/2005 | COM | Swisher | Promoted to active roster | | | Before |
| 8/26/2005 | FOR | Mantei | Released | | | Before |
| 8/26/2005 | FOR | Mateo | Released | | | Before |
| 8/26/2005 | FOR | Segui | Signed | | | Before |
| 8/26/2005 | FOR | Segui | Demoted to reserve roster | | | Before |
| 8/26/2005 | FOR | Smith | Signed | | | Before |
| 8/26/2005 | HEN | Davis | Demoted to reserve roster | | | Before |
| 8/26/2005 | HEN | Redmond | Promoted to active roster | | | Before |
| 8/26/2005 | HYS | Bedard | Promoted to active roster | | | Before |
| 8/26/2005 | HYS | Benoit | Promoted to active roster | | | Before |
| 8/26/2005 | HYS | Heilman | Demoted to reserve roster | | | Before |
| 8/26/2005 | HYS | Lopez | Promoted to active roster | | | Before |
| 8/26/2005 | HYS | Miller | Demoted to reserve roster | | | Before |
| 8/26/2005 | HYS | Molina,J | Promoted to active roster | | | Before |
| 8/26/2005 | HYS | Ross | Demoted to reserve roster | | | Before |
| 8/26/2005 | HYS | Woodward | Demoted to reserve roster | | | Before |
| 8/26/2005 | SYN | Dominguez | Promoted to active roster | | | Before |
| 8/26/2005 | SYN | Ludwick | Promoted to active roster | | | Before |
| 8/26/2005 | SYN | Mauer | Promoted to active roster | | | Before |
| 8/26/2005 | SYN | Reyes | Promoted to active roster | | | Before |
| 8/26/2005 | SYN | Soriano | Promoted to active roster | | | Before |
| 8/28/2005 | ANR | Bell | Promoted to active roster | | | Before |
| 8/28/2005 | ANR | Blackley | Promoted to active roster | | | Before |
| 8/28/2005 | ANR | Calero | Promoted to active roster | | | Before |
| 8/28/2005 | ANR | Gathright | Promoted to active roster | | | Before |
| 8/28/2005 | ANR | Jackson | Promoted to active roster | | | Before |
| 8/28/2005 | ANR | Johnson | Promoted to active roster | | | Before |
| 8/28/2005 | ANR | Keppinger | Promoted to active roster | | | Before |
| 8/28/2005 | ANR | Kieschnick | Promoted to active roster | | | Before |
| 8/28/2005 | ANR | Mohr | Promoted to active roster | | | Before |
| 8/28/2005 | ANR | Sexson | Promoted to active roster | | | Before |
| 8/28/2005 | BLU | Farnsworth | Promoted to active roster | | | Before |
| 8/28/2005 | BLU | Perez | Promoted to active roster | | | Before |
| 8/28/2005 | BLU | Perez | Promoted to active roster | | | Before |
| 8/28/2005 | BLU | Robinson | Promoted to active roster | | | Before |
| 8/28/2005 | BOU | Crede | Demoted to reserve roster | | | Before |
| 8/28/2005 | BOU | LeCroy | Demoted to reserve roster | | | Before |
| 8/28/2005 | BOU | Wells | Demoted to reserve roster | | | Before |
| 8/28/2005 | BST | Borders | Signed | | | Before |
| 8/28/2005 | BST | Burke | Demoted to reserve roster | | | Before |
| 8/28/2005 | BST | Burke | Promoted to active roster | | | Before |
| 8/28/2005 | BST | Cabrera | Promoted to active roster | | | Before |
| 8/28/2005 | BST | Colon | Promoted to active roster | | | Before |
| 8/28/2005 | BST | Cotts | Promoted to active roster | | | Before |
| 8/28/2005 | BST | Francisco | Promoted to active roster | | | Before |
| 8/28/2005 | BST | Guardado | Promoted to active roster | | | Before |
| 8/28/2005 | BST | Jordan | Released | | | Before |
| 8/28/2005 | BST | Martinez,A | Released | | | Before |
| 8/28/2005 | BST | Moeller | Signed | | | Before |
| 8/28/2005 | BST | Mussina | Promoted to active roster | | | Before |
| 8/28/2005 | BST | Vizcaino | Promoted to active roster | | | Before |
| 8/28/2005 | COM | Armas | Promoted to active roster | | | Before |
| 8/28/2005 | COM | Cota | Promoted to active roster | | | Before |
| 8/28/2005 | COM | Dreifort | Demoted to reserve roster | | | Before |
| 8/28/2005 | COM | Elarton | Promoted to active roster | | | Before |
| 8/28/2005 | COM | Fossum | Promoted to active roster | | | Before |
| 8/28/2005 | COM | Giambi | Activated from disabled list | | | Before |
| 8/28/2005 | COM | Gross | Demoted to reserve roster | | | Before |
| 8/28/2005 | COM | Gryboski | Promoted to active roster | | | Before |
| 8/28/2005 | COM | Patterson | Demoted to reserve roster | | | Before |
| 8/28/2005 | FOR | Barmes | Promoted to active roster | | | Before |
| 8/28/2005 | FOR | Cerda | Promoted to active roster | | | Before |
| 8/28/2005 | FOR | Hawpe | Promoted to active roster | | | Before |
| 8/28/2005 | FOR | McPherson | Promoted to active roster | | | Before |
| 8/28/2005 | FOR | Ohka | Promoted to active roster | | | Before |
| 8/28/2005 | FOR | Segui | Promoted to active roster | | | Before |
| 8/28/2005 | FOR | Sullivan | Promoted to active roster | | | Before |
| 8/28/2005 | FOR | Witasick | Promoted to active roster | | | Before |
| 8/28/2005 | HEG | Adams | Promoted to active roster | | | Before |
| 8/28/2005 | HEG | Brown | Promoted to active roster | | | Before |
| 8/28/2005 | HEG | Pierzynski | Promoted to active roster | | | Before |
| 8/28/2005 | HSX | Field | Released | | | Before |
| 8/28/2005 | HSX | Glynn | Signed | | | Before |
| 8/28/2005 | HSX | Graffanino | Promoted to active roster | | | Before |
| 8/28/2005 | HSX | Howard | Promoted to active roster | | | Before |
| 8/28/2005 | HSX | Inge | Promoted to active roster | | | Before |
| 8/28/2005 | HSX | Linden | Promoted to active roster | | | Before |
| 8/28/2005 | SLG | Betemit | Demoted to reserve roster | | | Before |
| 8/28/2005 | SLG | Hasegawa | Promoted to active roster | | | Before |
| 8/28/2005 | SLG | Hudson | Demoted to reserve roster | | | Before |
| 8/28/2005 | SLG | Kroeger | Promoted to active roster | | | Before |
| 8/28/2005 | SLG | Prior | Promoted to active roster | | | Before |
| 8/28/2005 | SLG | Restovich | Promoted to active roster | | | Before |
| 8/28/2005 | SYN | Kennedy | Demoted to reserve roster | | | Before |
| 8/28/2005 | SYN | Taveras | Demoted to reserve roster | | | Before |
| 8/29/2005 | BOU | Gagne | Demoted to reserve roster | | | Before |
| 8/31/2005 | SYN | Taveras | Promoted to active roster | | | Before |
| 9/1/2005 | FOR | Barmes | Demoted to reserve roster | | | Before |
| 9/1/2005 | FOR | Bigbie | Demoted to reserve roster | | | Before |
| 9/1/2005 | FOR | Laker | Demoted to reserve roster | | | Before |
| 9/1/2005 | FOR | McPherson | Demoted to reserve roster | | | Before |
| 9/1/2005 | FOR | Rincon | Demoted to reserve roster | | | Before |
| 9/1/2005 | FOR | Walker | Demoted to reserve roster | | | Before |
| 9/1/2005 | FOR | Wilson | Demoted to reserve roster | | | Before |
| 9/1/2005 | FOR | Wright | Demoted to reserve roster | | | Before |
| 9/1/2005 | HEN | Bennett,G | Demoted to reserve roster | | | Before |
| 9/1/2005 | HEN | Bennett,G | Promoted to active roster | | | Before |
| 9/1/2005 | HEN | Bennett,G | Demoted to reserve roster | | | Before |
| 9/1/2005 | HEN | Davis | Promoted to active roster | | | Before |
| 9/1/2005 | HEN | Garcia,D | Promoted to active roster | | | Before |
| 9/1/2005 | HEN | Glover | Promoted to active roster | | | Before |
| 9/1/2005 | HEN | Granderson | Promoted to active roster | | | Before |
| 9/1/2005 | HEN | Meyer | Promoted to active roster | | | Before |
| 9/1/2005 | HEN | Nelson | Promoted to active roster | | | Before |
| 9/1/2005 | HEN | Pratt | Promoted to active roster | | | Before |
| 9/1/2005 | HEN | Redmond | Demoted to reserve roster | | | Before |
| 9/1/2005 | HEN | Redmond | Promoted to active roster | | | Before |
| 9/1/2005 | HEN | Rhodes | Promoted to active roster | | | Before |
| 9/1/2005 | HEN | Shouse | Demoted to reserve roster | | | Before |
| 9/1/2005 | HEN | Shouse | Promoted to active roster | | | Before |
| 9/1/2005 | HEN | Stanford | Promoted to active roster | | | Before |
| 9/1/2005 | HEN | Thames | Promoted to active roster | | | Before |
| 9/1/2005 | HEN | Williamson | Demoted to reserve roster | | | Before |
| 9/1/2005 | HEN | Williamson | Promoted to active roster | | | Before |
| 9/1/2005 | HYS | Carrasco | Promoted to active roster | | | Before |
| 9/1/2005 | HYS | Francis | Promoted to active roster | | | Before |
| 9/1/2005 | HYS | Heilman | Promoted to active roster | | | Before |
| 9/1/2005 | HYS | Hill | Promoted to active roster | | | Before |
| 9/1/2005 | HYS | Mecir | Promoted to active roster | | | Before |
| 9/1/2005 | HYS | Miller | Promoted to active roster | | | Before |
| 9/1/2005 | HYS | Nivar | Promoted to active roster | | | Before |
| 9/1/2005 | HYS | Ross | Promoted to active roster | | | Before |
| 9/1/2005 | HYS | Tankersley | Promoted to active roster | | | Before |
| 9/1/2005 | HYS | Woodward | Promoted to active roster | | | Before |
| 9/3/2005 | BOU | McCracken | Signed | | | Before |
| 9/3/2005 | BOU | Weathers | Released | | | Before |
| 9/3/2005 | BST | Anderson | Demoted to reserve roster | | | Before |
| 9/3/2005 | BST | Burke | Demoted to reserve roster | | | Before |
| 9/3/2005 | BST | Francisco | Demoted to reserve roster | | | Before |
| 9/3/2005 | COM | Giambi | Demoted to reserve roster | | | Before |
| 9/3/2005 | COM | Patterson | Promoted to active roster | | | Before |
| 9/3/2005 | FOR | Laker | Released | | | Before |
| 9/3/2005 | FOR | McKay | Signed | | | Before |
| 9/3/2005 | FOR | Serrano | Signed | | | Before |
| 9/3/2005 | FOR | Sullivan | Released | | | Before |
| 9/3/2005 | FOR | Walker | Promoted to active roster | | | Before |
| 9/3/2005 | HSX | Young,C | Promoted to active roster | | | Before |
| 9/3/2005 | SLG | Abbott | Signed | | | Before |
| 9/3/2005 | SLG | Eischen | Demoted to reserve roster | | | Before |
| 9/3/2005 | SLG | Gregg | Released | | | Before |
| 9/3/2005 | SLG | Hancock | Released | | | Before |
| 9/3/2005 | SLG | Wilson | Signed | | | Before |
| 9/3/2005 | SYN | Wells | Demoted to reserve roster | | | Before |
| 9/7/2005 | BOU | Williams | Demoted to reserve roster | | | Before |
| 9/7/2005 | COM | Haren | Promoted to active roster | | | Before |
| 9/7/2005 | COM | Stinnett | Demoted to reserve roster | | | Before |
| 9/7/2005 | HEG | Garciaparra | Promoted to active roster | | | Before |
| 9/7/2005 | HEN | Pratt | Demoted to reserve roster | | | Before |
| 9/7/2005 | HSX | Gregg | Signed | | | Before |
| 9/7/2005 | HSX | Miceli | Released | | | Before |
| 9/7/2005 | HSX | Phelps | Released | | | Before |
| 9/7/2005 | HSX | Ramirez | Demoted to reserve roster | | | Before |
| 9/7/2005 | HSX | Seibel | Signed | | | Before |
| 9/7/2005 | SYN | Day | Promoted to active roster | | | Before |
| 9/7/2005 | SYN | German | Promoted to active roster | | | Before |
| 9/7/2005 | SYN | Soriano | Demoted to reserve roster | | | Before |
| 9/7/2005 | SYN | Tsao | Promoted to active roster | | | Before |
| 9/7/2005 | SYN | Valdez | Promoted to active roster | | | Before |
| 9/7/2005 | SYN | Wells | Promoted to active roster | | | Before |
| 9/8/2005 | ANR | Lofton | Demoted to reserve roster | | | Before |
| 9/8/2005 | HEN | Bennett,G | Promoted to active roster | | | Before |
| 9/12/2005 | FOR | Alvarez | Released | | | Before |
| 9/12/2005 | FOR | Batista | Demoted to reserve roster | | | Before |
| 9/12/2005 | FOR | Batista | Promoted to active roster | | | Before |
| 9/12/2005 | FOR | Cerda | Released | | | Before |
| 9/12/2005 | FOR | Collier | Signed | | | Before |
| 9/12/2005 | FOR | Diaz | Signed | | | Before |
| 9/12/2005 | FOR | Foulke | Demoted to reserve roster | | | Before |
| 9/12/2005 | FOR | Laker | Released | | | Before |
| 9/12/2005 | FOR | McKay | Signed | | | Before |
| 9/12/2005 | FOR | Serrano | Signed | | | Before |
| 9/12/2005 | FOR | Sullivan | Released | | | Before |
| 9/12/2005 | FOR | Sweeney | Demoted to reserve roster | | | Before |
| 9/12/2005 | FOR | Telemaco | Signed | | | Before |
| 9/12/2005 | FOR | Torres | Demoted to reserve roster | | | Before |
| 9/12/2005 | FOR | Walker | Demoted to reserve roster | | | Before |
| 9/12/2005 | FOR | Wilson | Released | | | Before |
| 9/12/2005 | FOR | Young,E | Demoted to reserve roster | | | Before |
| 9/12/2005 | SYN | Bacsik | Released | | | Before |
| 9/12/2005 | SYN | Bacsik | Signed | | | Before |
| 9/12/2005 | SYN | Corey | Signed | | | Before |
| 9/12/2005 | SYN | Day | Released | | | Before |
| 9/12/2005 | SYN | Day | Signed | | | Before |
| 9/12/2005 | SYN | Dominguez | Demoted to reserve roster | | | Before |
| 9/12/2005 | SYN | German | Demoted to reserve roster | | | Before |
| 9/12/2005 | SYN | Ludwick | Released | | | Before |
| 9/12/2005 | SYN | Ludwick | Signed | | | Before |
| 9/12/2005 | SYN | McCarty | Signed | | | Before |
| 9/12/2005 | SYN | Thornton | Signed | | | Before |
| 9/12/2005 | SYN | Tsao | Demoted to reserve roster | | | Before |
| 9/14/2005 | ANR | Takatsu | Demoted to reserve roster | | | Before |
| 9/14/2005 | BLU | Rivas | Promoted to active roster | | | Before |
| 9/14/2005 | BOU | Bennett,J | Signed | | | Before |
| 9/14/2005 | BOU | Kinney | Signed | | | Before |
| 9/14/2005 | BOU | Powell | Released | | | Before |
| 9/14/2005 | BOU | Rodriguez | Released | | | Before |
| 9/14/2005 | BST | Anderson | Promoted to active roster | | | Before |
| 9/14/2005 | BST | Burke | Promoted to active roster | | | Before |
| 9/14/2005 | BST | Francisco | Promoted to active roster | | | Before |
| 9/14/2005 | COM | Bard | Promoted to active roster | | | Before |
| 9/14/2005 | FOR | Alvarez | Released | | | Before |
| 9/14/2005 | FOR | Alvarez | Signed | | | Before |
| 9/14/2005 | FOR | Cerda | Released | | | Before |
| 9/14/2005 | FOR | Cerda | Signed | | | Before |
| 9/14/2005 | FOR | Collier | Released | | | Before |
| 9/14/2005 | FOR | Collier | Signed | | | Before |
| 9/14/2005 | FOR | Diaz | Released | | | Before |
| 9/14/2005 | FOR | Diaz | Signed | | | Before |
| 9/14/2005 | FOR | Telemaco | Released | | | Before |
| 9/14/2005 | FOR | Telemaco | Signed | | | Before |
| 9/14/2005 | FOR | Wilson | Released | | | Before |
| 9/14/2005 | FOR | Wilson | Signed | | | Before |
| 9/14/2005 | FOR | Yan | Demoted to reserve roster | | | Before |
| 9/14/2005 | HEG | Escobar | Signed | | | Before |
| 9/14/2005 | HEG | Santiago | Released | | | Before |
| 9/14/2005 | HSX | Bukvich | Signed | | | Before |
| 9/14/2005 | HSX | Howard | Demoted to reserve roster | | | Before |
| 9/14/2005 | HSX | Seibel | Released | | | Before |
| 9/14/2005 | HYS | Bedard | Demoted to reserve roster | | | Before |
| 9/14/2005 | HYS | Francis | Demoted to reserve roster | | | Before |
| 9/14/2005 | HYS | Greene | Demoted to reserve roster | | | Before |
| 9/14/2005 | SLG | Vogelsong | Demoted to reserve roster | | | Before |
| 9/14/2005 | SYN | Bacsik | Released | | | Before |
| 9/14/2005 | SYN | Day | Released | | | Before |
| 9/14/2005 | SYN | Hoffman | Demoted to reserve roster | | | Before |
| 9/14/2005 | SYN | Ludwick | Released | | | Before |
| 9/14/2005 | SYN | Reyes | Demoted to reserve roster | | | Before |
| 9/16/2005 | SYN | Soriano | Demoted to reserve roster | | | Before |
| 9/18/2005 | COM | Colon | Demoted to reserve roster | | | Before |
| 9/18/2005 | COM | Snell | Promoted to active roster | | | Before |
| 9/18/2005 | COM | Wolf | Demoted to reserve roster | | | Before |
| 9/18/2005 | HEG | Escobar | Signed | | | Before |
| 9/18/2005 | HEG | Santiago | Released | | | Before |
| 9/18/2005 | HYS | Choi | Demoted to reserve roster | | | Before |
| 9/18/2005 | HYS | Choi | Promoted to active roster | | | Before |
| 9/18/2005 | HYS | Greene | Promoted to active roster | | | Before |
| 9/18/2005 | HYS | Heilman | Demoted to reserve roster | | | Before |
| 9/18/2005 | HYS | Tankersley | Demoted to reserve roster | | | Before |
| 9/18/2005 | SYN | Cook | Demoted to reserve roster | | | Before |
| 9/18/2005 | SYN | Embree | Demoted to reserve roster | | | Before |
| 9/19/2005 | BLU | Floyd | Promoted to active roster | | | Before |
| 9/19/2005 | BOU | Bartlett | Promoted to active roster | | | Before |
| 9/19/2005 | BOU | Beckett | Demoted to reserve roster | | | Before |
| 9/19/2005 | BOU | Beckett | Promoted to active roster | | | Before |
| 9/19/2005 | BOU | LeCroy | Promoted to active roster | | | Before |
| 9/19/2005 | FOR | Foulke | Promoted to active roster | | | Before |
| 9/19/2005 | FOR | Torres | Promoted to active roster | | | Before |
| 9/19/2005 | FOR | Young,E | Promoted to active roster | | | Before |
| 9/19/2005 | HSX | Brito | Released | | | Before |
| 9/19/2005 | HSX | Brooks | Signed | | | Before |
| 9/19/2005 | HSX | Colome | Demoted to reserve roster | | | Before |
| 9/19/2005 | HSX | Dohmann | Signed | | | Before |
| 9/19/2005 | HSX | Glynn | Released | | | Before |
| 9/19/2005 | HSX | Kline | Demoted to reserve roster | | | Before |
| 9/19/2005 | HSX | Wagner | Demoted to reserve roster | | | Before |
| 9/19/2005 | SLG | Blanton | Promoted to active roster | | | Before |
| 9/19/2005 | SLG | Eischen | Promoted to active roster | | | Before |
| 9/19/2005 | SLG | Wagner | Promoted to active roster | | | Before |
| 9/19/2005 | SYN | Bauer | Signed | | | Before |
| 9/19/2005 | SYN | McCarty | Released | | | Before |
| 9/20/2005 | FOR | Foulke | Demoted to reserve roster | | | Before |
| 9/20/2005 | FOR | Yan | Demoted to reserve roster | | | Before |
| 9/21/2005 | FOR | Neal | Demoted to reserve roster | | | Before |
| 9/21/2005 | FOR | Torres | Demoted to reserve roster | | | Before |
| 9/21/2005 | FOR | Young,E | Demoted to reserve roster | | | Before |
| 9/21/2005 | SYN | Valdez | Demoted to reserve roster | | | Before |
| 9/21/2005 | SYN | Zambrano | Demoted to reserve roster | | | Before |
| 9/23/2005 | SYN | Bauer | Demoted to reserve roster | | | Before |
| 9/23/2005 | SYN | Cook | Promoted to active roster | | | Before |
| 9/23/2005 | SYN | Corey | Demoted to reserve roster | | | Before |
| 9/23/2005 | SYN | Dominguez | Promoted to active roster | | | Before |
| 9/23/2005 | SYN | Embree | Promoted to active roster | | | Before |
| 9/23/2005 | SYN | Fultz | Demoted to reserve roster | | | Before |
| 9/23/2005 | SYN | Fultz | Promoted to active roster | | | Before |
| 9/23/2005 | SYN | Hoffman | Promoted to active roster | | | Before |
| 9/23/2005 | SYN | Kennedy | Promoted to active roster | | | Before |
| 9/23/2005 | SYN | Mauer | Demoted to reserve roster | | | Before |
| 9/23/2005 | SYN | Mauer | Promoted to active roster | | | Before |
| 9/23/2005 | SYN | Thornton | Demoted to reserve roster | | | Before |
| 9/23/2005 | SYN | Valentin | Demoted to reserve roster | | | Before |
| 9/23/2005 | SYN | Zambrano | Promoted to active roster | | | Before |
| 9/25/2005 | HEG | Adams | Demoted to reserve roster | | | Before |
| 9/25/2005 | HEG | Brown | Demoted to reserve roster | | | Before |
| 9/25/2005 | HEG | Carrara | Promoted to active roster | | | Before |
| 9/25/2005 | HEG | Easley | Promoted to active roster | | | Before |
| 9/25/2005 | HEG | Escobar | Demoted to reserve roster | | | Before |
| 9/25/2005 | HEG | Gonzalez | Demoted to reserve roster | | | Before |
| 9/25/2005 | HEG | Harang | Demoted to reserve roster | | | Before |
| 9/25/2005 | HEG | Molina | Demoted to reserve roster | | | Before |
| 9/25/2005 | HEG | Ojeda | Promoted to active roster | | | Before |
| 9/25/2005 | HEG | Rusch | Promoted to active roster | | | Before |
| 9/25/2005 | HEG | Ward | Demoted to reserve roster | | | Before |
| 9/25/2005 | HEG | Wright | Demoted to reserve roster | | | Before |
| 9/25/2005 | HEN | Bennett,G | Demoted to reserve roster | | | Before |
| 9/25/2005 | HEN | Garcia,D | Demoted to reserve roster | | | Before |
| 9/25/2005 | HEN | Glover | Demoted to reserve roster | | | Before |
| 9/25/2005 | HEN | Granderson | Demoted to reserve roster | | | Before |
| 9/25/2005 | HEN | Long | Demoted to reserve roster | | | Before |
| 9/25/2005 | HEN | Long | Promoted to active roster | | | Before |
| 9/25/2005 | HEN | Meyer | Demoted to reserve roster | | | Before |
| 9/25/2005 | HEN | Nelson | Demoted to reserve roster | | | Before |
| 9/25/2005 | HEN | Pratt | Promoted to active roster | | | Before |
| 9/25/2005 | HEN | Rhodes | Demoted to reserve roster | | | Before |
| 9/25/2005 | HEN | Stanford | Demoted to reserve roster | | | Before |
| 9/25/2005 | HEN | Tomko | Demoted to reserve roster | | | Before |
| 9/25/2005 | HEN | Williamson | Demoted to reserve roster | | | Before |
| 9/25/2005 | SYN | Mauer | Demoted to reserve roster | | | Before |
| 9/25/2005 | SYN | Valentin | Promoted to active roster | | | Before |
| 9/30/2005 | BLU | Diaz | Demoted to reserve roster | | | Before |
| 9/30/2005 | BLU | Leicester | Demoted to reserve roster | | | Before |
| 9/30/2005 | BLU | Perez | Demoted to reserve roster | | | Before |
| 9/30/2005 | BLU | Perez | Demoted to reserve roster | | | Before |
| 9/30/2005 | BLU | Rivas | Demoted to reserve roster | | | Before |
| 9/30/2005 | BLU | Robinson | Demoted to reserve roster | | | Before |
| 10/2/2005 | HEN | Bennett,G | Promoted to active roster | | | Before |
| 10/2/2005 | HEN | Davis | Demoted to reserve roster | | | Before |
| 10/7/2005 | SYN | Mauer | Promoted to active roster | | | Before |
| 10/15/2005 | HEN | Shouse | Demoted to reserve roster | | | Before |
| 10/15/2005 | HEN | Williamson | Promoted to active roster | | | Before |
| 10/20/2005 | SYN | Contreras | Traded away | SCO | | After |
| 10/20/2005 | SYN | Contreras | Acquired via trade | SCO | | After |
| 10/20/2005 | SYN | Rolen | Traded away | SCO | | After |
| 10/20/2005 | SYN | Rolen | Acquired via trade | SCO | | After |